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Table 2 Randomized trials reporting treatment of gingival recession

From: Efficacy of concentrated growth factor (CGF) in the surgical treatment of oral diseases: a systematic review and meta-analysis

Author (year)

Study Design, Blinded (duration)

Population

Intervention (number of surgical sites)

No. of participants (sites)

Age (mean/range)

gender

Control (sites)

Test (sites)

Bozkurt et al. (2015) [29]

Split-mouth, examiner-blinded (6 months)

20 (119)

37.1 ± 1.03 (20–45)

7 M/13F

CAF (59)

CAF + CGF (60)

Akcan et al. (2020) [55]

Split-mouth, N (6 months)

19 (74)

N (20–63)

11 M/8F

CAF + CTG (37)

CAF + CGF (37)

Korkmaz et al. (2021) [59]

Parallel, examiner-blinded (6 months)

40 (108)

41.1 ± 9.3 (26–63)

N

TT + CTG (51)

TT + CGF (57)

Xue et al. (2022) [67]

Parallel, N (6 months)

28 (70)

38.56 ± 9.28 (N)

17 M/11F

CAT + CTG (34)

CAT + CGF (36)

Öngöz et al. (2023) [46]

Parallel, examiner-blinded (6 months)

16 (45)

35.31 ± 5.55 (25–45)

8 M/8F

CAF (15)

T1: CAF + CGF (15); T2: CAF + PRF (15)

  1. CAF: coronally advanced flap; CTG: connective tissue graft; CGF: concentrated growth factor; TT: tunnel technique; N: not mentioned