Table 3 Randomized trials reporting alveolar ridge preservation
Author (year) | Study Design, Blinded (duration) | Population | Intervention (number of surgical sites) | ||||
|---|---|---|---|---|---|---|---|
No. of participants (sites) | Age (mean/range) | gender | Control (sites) | Test (sites) | |||
Lin et al. (2021) [60] | Parallel, N (8 months) | 36 (36) | 48 (34–65) | 21 M/15F | natural healing (12) | T1: BO + collagen membrane (12); T2: BO + CGF + CGF membrane (12) | |
Ma et al. (2021) [45] | Parallel, examiner-blinded (3 months) | 46 (46) | 43.98 ± 13.8 (23–72) | 28 M/18F | natural healing (23) | CGF + CGF membrane (23) | |
Keranmu et al. (2022) [58] | Parallel, N (6 months) | 38 (38) | 28.89 ± 2.7 (N) | 15 M/23F | BO + collagen membrane (19) | BO + CGF + CGF membrane + collagen membrane (19) | |
Liu et al. (2022) [61] | Parallel, N (6months) | 22 (24) | 30.46 ± 10.58 (19–61) | 11 M/11F | BO + collagen membrane (12) | BO + CGF membrane (12) | |
Elayah et al. (2023) [51] | Split-mouth, examiner-blinded (3 months) | 30 (60) | 25 ± 0.5 (19–35) | 16 M/14F | natural healing (30) | CGF (30) | |