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Table 1 Distribution of characteristics among children with JIA and controls at both visits

From: Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis – a prospective multicenter cohort study

Variable

Children—First Visit

Children—Two-Year Follow-up

JIA

Controls

JIA

Controls

%

(n/N)

%

(n/N)

p-valuea

%

(n/N)

%

(n/N)

p-valuea

Median age at visit, years (IQR)

7.6

(6.7–8.9)

7.8

(6.8–9.1)

 

9.7

(8.6–10.9)

9.8

(8.9–11.0)

 

Female gender

70.2

(33/47)

75.9

(41/54)

      

Toothbrushing, twice a day or more

68.1

(32/47)

75.9

(41/54)

0.380

71.7

(33/46)

82.7

(43/52)

0.195

Tooth flossing, several times a week or more

10.6

(5/47)

11.3

(6/53)

1.000

17.8

(8/46)

11.8

(6/51)

0.431

Gingival bleeding during toothbrushing, sometimes or more

43.5

(20/46)

33.3

(18/54)

0.298

50.0

(23/46)

33.3

(17/51)

0.096

Pain or discomfort during toothbrushing

6.4

(3/47)

1.9

(1/54)

0.336

8.7

(4/46)

0

(0/51)

0.047

Ulcerations, several times yearly or more

31.1

(14/45)

13.0

(7/54)

0.028

32.6

(15/46)

16.0

(8/50)

0.057

Orofacial pain ever

27.7

(13/47)

11.1

(6/54)

0.034

31.9

(15/47)

5.6

(3/54)

0.001

Orofacial pain last 30 days

14.9

(7/47)

1.9

(1/54)

0.024

21.3

(10/47)

3.7

(2/54)

0.011

Caries, d1-5f/D1-5F-level > 0

26.1

(12/46)

27.8

(15/54)

0.849

37.0

(17/46)

33.3

(18/54)

0.243

JIA disease characteristics

 Median age at disease onset, years (IQR)

2.4

(1.8–4.8)

        

 Disease duration, median years (IQR)

4.5

(3.1–5.9)

   

6.5

(5.1–7.8)

   

 Polyarticular disease course (> 4 affected joints)

48.9

(23/47)

   

48.9

(23/47)

   

 Oligoarticular JIA category1

51.1

(24/47)

   

51.1

(24/47)

   

 DMARDs ongoing

72.3

(34/47)

   

66.0

(31/47)

   

 Active joints > 0

17.0

(8/47)

   

10.6

(5/47)

   

 MDglobalVAS > 0

34.0

(16/47)

   

21.7

(10/46)

   

 ESR ≥ 20 mm/h

2.2

(1/46)

   

2.1

(1/47)

   

 PRglobalVAS > 0

72.3

(34/47)

   

61.7

(29/47)

   

 VAS global pain > 0

51.1

(24/47)

   

74.5

(35/47)

   

 CHAQ > 0

66.0

(31/47)

   

59.6

(28/47)

   

 JADAS ≥ 1

70.2

(33/47)

   

63.0

(29/46)

   

 TMJ involvement ever2

23.4

(11/47)

   

27.7

(13/47)

   

 TMJ involvement at study visit2

4.3

(2/47)

   

2.1

(1/47)

   
  1. Differences between JIA and Control group: achi-square test/Fisher’s exact
  2. 1JIA category – oligo arthritis (including persistent n = 19 and extended n = 5) vs non oligo arthritis (including systemic onset n = 2, polyarthritis RFn = 12, polyarthritis RF+n = 0, psoriatic JIA n = 2, enthesitis related arthritis n = 2 and undifferentiated n = 5.
  3. 2TMJ involvement as recorded clinically by the pediatric rheumatologist
  4. JIA Juvenile idiopathic arthritis, IQR interquartile range, n/N number observed/total number assessed for each variable, excluding missing values (total participants N = 47 JIA and N = 54 Controls), d1-5f/D1-5F  decayed and filled deciduous/ permanent teeth, enamel caries included, DMARDs disease-modifying antirheumatic drugs (synthetic and/or biologic agents), MDglobalVAS Physician's global assessment of disease activity, ESR Erythrocyte sedimentation rate, VAS Visual analog scale, PRglobalVAS Parent's global assessment of disease activity, CHAQ Childhood Health Assessment Questionnaire, JADAS juvenile arthritis disease activity score, TMJ temporomandibular joint. P-values < 0.05 are marked in bold