Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis – a prospective multicenter cohort study

Table 5 Orofacial pain, impaired CHQ, disease activity, and TMJ-arthritis in relation to OHRQoL impacts in children

	First visit ECOHIS > 0							Two-year follow-up ECOHIS > 0
	Unadjusted regressions				Adjusted regressions^a			Unadjusted regressions				Adjusted regressions^a
	n	OR	95%CI	p-value	OR	95%CI	p-value	n	OR	95%CI	p-value	OR	95%CI	p-value
All children (with and without JIA)
Orofacial pain – EVER^b
No	82	Ref			Ref			83	Ref
Yes	19	3.9	0.8–18.4	0.080	3.1	0.7–15.1	0.155	18	*			*
CHQ physical score impaired
No	87	Ref			Ref			82	Ref
Yes	9	3.2	0.4–27.1	0.281	1.9	0.2–18.0	0.575	14	4.2	0.5–34.1	0.180	3.6	0.4–31.1	0.247
Children with JIA only
JADAS 71 > 0
No	13	Ref			Ref			17	Ref
Yes	33	2.5	0.5–11.3	0.238	2.8	0.5–15.7	0.254	29	1.3	0.3–6.9	0.726	1.5	0.3–7.9	0.665
TMJ involvement – EVER^b
No	36	Ref			Ref			34	Ref
Yes	11	*			*			13	2.6	0.3–23.7	0.405	4.0	0.4–42.2	0.249

Unadjusted and adjusted ordinal logistic regressions including both children with and without JIA for orofacial pain and CHQ physical score
^aadjusted for group affiliation (JIA/Controls) when both children with and without JIA were included, gender and educational level of mother and father. ^bdue to the missing timeframe of ECOHIS the occurrence of orofacial pain –ever, and TMJ involvement –ever (as recorded clinically by the pediatric rheumatologist) was used in these analyses for children
*Informative model results not available (N/A) from the model because of a perfect correlation, all children with orofacial pain/TMJ arthritis have ECOHIS > 0
CHQ child health questionnaire, TMJ temporomandibular joint, OHRQoL oral health related quality of life, ECOHIS early childhood oral health impaction scale, n number, OR odds ratio, CI confidence interval, JIA juvenile idiopathic arthritis, JADAS juvenile arthritis disease activity score. P-values < 0.05 are marked in bold

ISSN: 1472-6831