Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis – a prospective multicenter cohort study

Table 6 Orofacial pain, impaired CHQ, disease activity, and TMJ-arthritis in relation to OHRQoL impacts in adolescents

	First visit Child OIDP > 0							Two-year follow-up Child OIDP > 0
	Unadjusted regressions				Adjusted regressions^a			Unadjusted regressions				Adjusted regressions^a
	n	OR	95%CI	p-value	OR	95%CI	p-value	n	OR	95%CI	p-value	OR	95%CI	p-value
Adolescents with and without JIA
Orofacial pain the last 30 days^b
No	159	Ref			Ref			162	Ref			Ref
Yes	33	4.2	1.9–9.3	< *0.001*	4.0	1.6–10.0	*0.003*	30	5.3	2.1–13.1	< *0.001*	5.3	1.9–14.9	*0.001*
CHQ physical score impaired
No	136	Ref			Ref			130	Ref			Ref
Yes	21	2.6	1.0–6.9	0.055	3.0	1.0–9.4	0.055	27	3.4	1.2–9.8	*0.021*	5.1	1.2–20.8	*0.024*
Adolescents with JIA
JADAS 71 > 0
No	36	Ref			Ref			37	Ref			Ref
Yes	61	5.8	1.6–21.1	*0.008*	5.1	1.3–19.6	*0.017*	60	2.3	0.6–8.8	0.239	1.8	0.4–7.6	0.418
TMJ involvement at study visit^b
No	93	Ref			Ref			98	Ref			Ref
Yes	12	12.5	3.1–50.9	< *0.001*	8.5	2.0–37.0	*0.004*	7	2.6	0.5–14.9	0.279	1.8	0.3–11.1	0.526

Unadjusted and adjusted ordinal logistic regressions including both adolescents with and without JIA for orofacial pain and CHQ physical score
^aadjusted for group affiliation (JIA/Controls) when both adolescents with and without JIA were included, gender and educational level of mother and father. ^bdue to the timeframe of Child OIDP (last three month) the occurrence of orofacial pain – last 30 days and TMJ involvement – at study visit (as recorded clinical by the pediatric rheumatologist) was used in these analyses for adolescents
CHQ child health questionnaire, TMJ temporomandibular joint, OHRQoL oral health related quality of life, Child OIDP child oral impact on daily performance, N number, OR odds ratio, CI confidence interval, JIA juvenile idiopathic arthritis, JADAS juvenile arthritis disease activity score. P-values < 0.05 are marked in bold

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