Table 3 Mendelian randomization estimates of the causal association between PD and serum lipid profile using IVW/Wald ratio method
Exposure | Outcome | OR (95% CI) | P value |
|---|---|---|---|
HDL | PD(GLIDE) | 0.91(0.82–0.99) | 0.04 |
LDL |  | 1.06(0.98–1.15) | 0.14 |
TC |  | 1.05(0.96–1.14) | 0.29 |
TG |  | 0.97(0.87–1.08) | 0.56 |
HDL | CP(FinnGen) | 1.08(0.94–1.24) | 0.26 |
LDL |  | 0.93(0.83–1.03) | 0.17 |
TC |  | 0.98(0.87–1.11) | 0.77 |
TG |  | 1.05(0.88–1.24) | 0.59 |
HDL | PD(GCST90018897) | 0.97(0.88–1.04) | 0.28 |
LDL |  | 1.11(1.02–1.19) | 0.01 |
TC |  | 1.02(0.93–1.12) | 0.69 |
TG |  | 1.03(0.95–1.11) | 0.50 |
PD(GLIDE) | HDL | 0.86(0.75–0.97) | 0.02 |
|  | LDL | 1.06(0.92–1.23) | 0.40 |
|  | TC | 0.99(0.87–1.14) | 0.98 |
|  | TG | 1.06(0.94–1.21) | 0.31 |
CP(FinnGen) | HDL | 1.03(0.95–1.12) | 0.36 |
|  | LDL | 0.96(0.87–1.05) | 0.33 |
|  | TC | 0.99(0.91–1.08) | 0.92 |
|  | TG | 1.02(0.95–1.11) | 0.48 |
PD(GCST90018897) | HDL | 1.02(0.97–1.08) | 0.46 |
|  | LDL | 1.01 (0.95–1.08) | 0.74 |
|  | TC | 1.03(0.96–1.09) | 0.34 |
|  | TG | 1.01(0.91–1.11) | 0.85 |