Does the application of autologous injectable Platelet-Rich Fibrin (i-PRF) affect the patient’s daily performance during the retraction of upper canines? A single-centre randomized split-mouth controlled trial

Table 5 Significance tests results for pairwise comparisons between the four evaluated times for patient-reported outcome measures in the injectable platelet-rich fibrin group

Time		Pain	Discomfort	Swelling	Difficulty in chewing
T1	T1-T2	0.001*	0.018	0.001*	0.102
	T1-T3	< 0.001*	0.002*	< 0.001*	0.028
	T1-T4	< 0.001*	0.001*	< 0.001*	0.003*
T2	T2-T3	0.003*	0.021	0.001*	0.014
T2	T2-T4	0.002*	0.001*	0.001*	0.003*
T3	T3-T4	0.063	0.042	0.016	0.010

Wilcoxon Signed-Ranks Tests were employed for pairwise comparisons, Bonferroni’s Adjustment of Alpha Level (i.e., 0.05/6 = 0.008)
T1 is 1 h after the injection; T2 is 2 h after the injection; T3 is 6 h after the injection; T4 is 24 h after the injection
^*Significant difference when P < 0.008

ISSN: 1472-6831