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Table 1 Qualitative Synthesis Results

From: Importance of periodontal phenotype in periodontics and restorative dentistry: a systematic review

Sl. No

Citation

No.

Type of study

Kind of

Clinical trial

Number of

Participants

Intervention

Outcome measures and summary

1

[16]

Review

A Literature Review

-

Gingival health

Subjects with thin and narrow gingiva tend to have more gingival recession compared with those with thick and wide gingiva.

2

[17]

Review

A Systematic review

-

Graft material

It was observed that any graft material was able to significantly enhance gingival thickness (GT).

3

[23]

Review

A Meta- regression analysis

-

Periodontal flap technique

Soft tissue thickness (STT) plays a limited role in predicting root coverage across all approaches; when flaps are performed with no graft, the effect of STT is most critical.

4

[24]

An original research

A randomized controlled clinical trial

30

Connective tissue graft

Both procedures were effective for root coverage at single RT1 recession with previously restored cement-enamel junction (CEJ). Adding a connective tissue graft (CTG) under CAF should be considered for Rec with thin gingival phenotype.

5

[25]

Case report

Case report

1

Periodontal Accelerated Osteogenic Orthodontics

In patients with dentofacial deformities and a thin periodontal phenotype, multi-disciplinary treatment that includes periodontal accelerated osteogenic orthodontics (PAOO) could be effective, and could improve both the quality and safety of orthodontic-orthognathic therapy.

6

[15]

A Review

A cluster analysis

-

Sagittal craniofacial profile

A moderate correlation was found between mandibular gingival thickness and the sagittal craniofacial profile. Patients with a concave craniofacial profile had a smaller keratinized gingiva width and gingival thickness in the aesthetic zone.

7

[28]

A Review

A Review

-

Allogenous dermal matrix

Allogenous dermal matrix (ADM) is a viable option for soft tissue augmentation, as well as for treatment approaches involving buccal bone gain.

8

[29]

An original research

A randomized controlled clinical trial

60

Sub-epithelial connective tissue graft,

Leukocyte- and platelet-rich fibrin membrane

All the three surgical techniques for root coverage: the coronally advanced flap (CAF), with a sub-epithelial connective tissue graft (SCTG) or with leukocyte- and platelet-rich fibrin (L-PRF) membranes produced significant gingival recession (GR) reduction and clinical attachment level (CAL) gain

9

[31]

An original research

A randomized controlled clinical trial

20

Mini-Five Gracey Curettes

The use of Mini-Five Gracey Curettes (MFC) resulted in a greater pocket depth (PD) reduction and lower rate of recession depth (RD) in the short term.

10

[32]

An original research

A multicenter inter- and intra-examiner agreement study

28

2018 Classification of Gingival Recession Defects and Gingival Phenotype

The 2018 Classification of Gingival Recession Defects and Gingival Phenotype is clinically reproducible within the examiners, and when the variables forming the matrix are analyzed individually.

11

[33]

An original research

A randomized controlled clinical trial

50

Modified coronally advanced tunnel technique

Both the modified coronally advanced tunnel technique (MCAT) and free gingival grafts (FGG) were successful in terms of gingival phenotype modification in the anterior mandible.

12

[39]

A Review

A narrative review

-

Periodontal outcomes

Periodontal diagnostic criteria should be thoroughly reviewed before fixed restorative treatments are planned and executed.

13

[40]

A Review

A consensus statement

-

Modification of gingiva

Patients with thin gingival tissue and mucogingival defects may benefit from phenotype modification therapy (PhMT-s) intervention and may require a secondary procedure to achieve optimal outcomes.

14

[42]

An original research

A comparative cohort study

28

Soft tissue phenotype modification

Soft tissue phenotype modification, either pouch roll or modified roll technique, during uncovering surgery resulted in favorable clinical outcomes.

15

[43]

An original research

A retrospective study

111

Connective tissue grafting

Surgical modification of peri-implant soft tissue phenotype via phenotype modification therapy (PhMT-s) may decrease the amount of mucosal recession (MR).

16

[45]

An original research

Description of surgical technique

1

Omega roll envelope flap

The omega roll envelope flap technique has shown advantages as maximizes the amount of connective tissue that can be rolled within the buccal flap.

17

[46]

A case series

A prospective case series

10

Microsurgical roll-in-envelope flap

In presence of sufficient periimplant supporting tissues and when indicated, the roll-in-envelope flap (RIE) seems to yield superior outcomes reducing pain/discomfort compared to connective tissue grafts.

18

[49]

An original research

A randomized controlled clinical trial

26

Zirconia abutments

Zirconia abutments exhibited better results than titanium abutments in terms of the peri-implant tissues. Moreover, in those with a thin phenotype, zirconia provided improved gingival esthetics.

19

[50]

A case series

A Retrospective Case Series

14

Vestibular Incision Subperiosteal Tunnel Access

Treatment of multiple gingival recession defects with vestibular incision subperiosteal tunnel access (VISTA) and subepithelial connective tissue grafts (SCTG) led to stable gingival thickness gains and shows promise as a strategy for phenotype modification therapy.

20

[51]

An original research

A Controlled Clinical Trial

41

Connective tissue graft

There are no significant differences in the outcomes of immediate implant placement for patients with different soft tissue phenotypes.