Fig. 5

With CRS, overexpression of ALDH3A1 restrain tumor growth in Xenograft models of OSCC. a Body weight curve of CRS + NC and CRS + Lv-ALDH3A1 groups. b Growth curves of tumor volume. c Tumor nodules of mice xenografts. d Tumor tissues weight were determined. e mRNA expression of tumor regulatory factors and EMT-related markers in tumor tissues were determined by RT- PCR. f Representative images of ALDH3A1, proliferation markers, tumor regulatory factors and EMT-related markers protein levels in tumors were assessed by immunohistochemical staining. Scale bar, 20 μm. Data are expressed as mean ± SD; *, P < 0.05; **, P < 0.01; ***, P < 0.001