Fig. 5
From: The role of cannabinoid receptor 2 in bone remodeling during orthodontic tooth movement
Quantitative analysis of immunohistochemistry of RANKL and OPG in the M1 pressure area after OTM in CB2.−/− and WT mice. a, b IHC of OPG /RANKL staining results in the distal root compression side of the first molar mice. Scale bar: 50 µm. R, root; PDL, periodontal ligament; AB, alveolar; ↑ (Blue arrow), RANKL-positive mononuclear cells ↑ (Red arrow), RANKL-positive multinuclear cells. c Illustration of the M1 pressure area after OTM. F: The direction of orthodontic force. d Statistic evaluation of the OPG /RANKL AOD in ROI, data were shown as mean ± standard deviation. Values were means ± SD.**** P < 0.0001