Association between life’s essential 8 and periodontitis: a population-based study

BMC Oral Health

Table 4 Association between LE8 and periodontitis stratified by cardiovascular disease

Exposure	Model I (OR, 95% CI, P-value)	Model II (OR, 95% CI, P-value)	Model III (OR, 95% CI, P-value)
With cardiovascular disease
LE8 score	0.988 (0.978, 0.999) 0.028	0.986 (0.975, 0.997) 0.014	0.998 (0.982, 1.014) 0.802
LE8 score, (groups)
Low (LE8 < 50)	1.0	1.0	1.0
Moderate (50 ≤ LE8 < 80)	0.893 (0.632, 1.263) 0.523	0.819 (0.569, 1.179) 0.283	0.851 (0.506, 1.432) 0.544
High (LE8 ≥ 80)	0.492 (0.273, 0.885) 0.018	0.437 (0.235, 0.813) 0.009	0.813 (0.345, 1.920) 0.637
Without cardiovascular disease
LE8 score	0.969 (0.966, 0.973) < 0.001	0.976 (0.972, 0.979) < 0.001	0.984 (0.980, 0.989) < 0.001
LE8 score, (groups)
Low (LE8 < 50)	1.0	1.0	1.0
Moderate (50 ≤ LE8 < 80)	0.575 (0.501, 0.662) < 0.001	0.578 (0.497, 0.670) < 0.001	0.727 (0.604, 0.874) 0.001
High (LE8 ≥ 80)	0.259 (0.219, 0.305) < 0.001	0.342 (0.286, 0.409) < 0.001	0.529 (0.423, 0.661) < 0.001

LE8, Life’s Essential 8; OR, odds ratio; CI, confidence interval
Model I was unadjusted
Model II was adjusted for sex; age; and race
Model III was adjusted for sex; age; race; annual family income; education level; marital status; floss use; alcohol consumption; depression; arthritis; asthma; and gout

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