| EMD and DPBM (mean 1.3 defects/patient) |  | EMD alone (mean 3.7 defects/patient) | p-value | ||
---|---|---|---|---|---|---|
n | % | n | % | |||
Number of patients | 133 | 100.0 | Â | 43 | 100.0 | Â |
Sex | Â | Â | Â | Â | Â | Â |
 Male | 84 | 63.2 |  | 31 | 72.1 | 0.285 |
 Female | 49 | 36.8 |  | 12 | 27.9 |  |
Age (mean ± SD, years) | 55.4 ± 8.9 |  |  | 52.8 ± 8.9 |  | 0.106 |
Diabetes mellitus | 3 | 2.3 | Â | 4 | 9.3 | 0.040* |
Hypertension | 24 | 18.0 | Â | 6 | 14.0 | 0.536 |
Smoking status | Â | Â | Â | Â | Â | Â |
 Non-smoker | 115 | 86.5 |  | 41 | 95.3 | 0.111 |
 Current smoker (< 20 cigarettes per day) | 18 | 13.5 |  | 2 | 4.7 |  |
Follow-up time (mean ± SD, months) | 58.5 ± 11.2 |  |  | 58.9 ± 11.2 |  | 0.863 |
Number of treatment sites | 175 | 100.0 | Â | 158 | 100.0 | Â |
Defect morphology | Â | Â | Â | Â | Â | Â |
 One-wall | 42 | 24.0 |  | 60 | 38.0 | 0.003** |
 Two-wall | 70 | 40.0 |  | 39 | 24.7 |  |
 Thress-wall | 63 | 36.0 |  | 59 | 37.3 |  |