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Fig. 3 | BMC Oral Health

Fig. 3

From: Photobiomodulation therapy’s impact on angiogenesis and osteogenesis in orthodontic tooth movement: in vitro and in vivo study

Fig. 3

The Impact of PBMT on Angiogenesis in Co-Culture Systems. A Representative images of tube formation in MC3T3-E1, HUVEC, and MC3T3-E1/HUVEC co-culture systems under light microscopy (100x magnification, scale bars represent 100 μm). B Quantification of the number of tubular branches in each experimental group (**: P < 0.01, **: P < 0.001; compared to the MC3T3-E1 group; #: P < 0.05; compared to the HUVEC group). C Statistical analysis of the total length of tubular branches in each experimental group (: P < 0.05, **: P < 0.001; compared to the MC3T3-E1 group; #: P < 0.05; compared to the HUVEC group). D-E Measurement of HIF-1α and VEGF expression levels by qRT-PCR (: P < 0.05, **: P < 0.01, ***: P < 0.001; compared to the HUVEC group; #: P < 0.05, ##: P < 0.01; compared to the MC3T3-E1 + HUVEC group)

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BMC Oral Health

ISSN: 1472-6831

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