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Fig. 1 | BMC Oral Health

Fig. 1

From: BML-111 inhibit H2O2-induced pyroptosis and osteogenic dysfunction of human periodontal ligament fibroblasts by activating the Nrf2/HO-1 pathway

Fig. 1

Effects of different concentrations of BML-111 and H2O2 on the cell viability of hPDLFs.

(A) Cell viability of hPDLFs treated with 0, 125, 250, 500, 1000 µM H2O2 for 4 h; (B) Cell viability of hPDLFs treated with 0, 5, 10, 20, 30 µM BML-111 for 24 h; (C) Cell viability of hPDLFs pretreated with 0, 5, 10, 20 µM BML-111 for 24 h and treated with 500 µM H2O2 for 4 h. Data were shown as mean ± SD from three experiments independently **P < 0.01 vs. control group, *P < 0.05 vs. control group, ##P < 0.01 vs. H2O2 group, #P < 0.05 vs. H2O2 group, nsP>0.05 vs. control group

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