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Fig. 7 | BMC Oral Health

Fig. 7

From: BML-111 inhibit H2O2-induced pyroptosis and osteogenic dysfunction of human periodontal ligament fibroblasts by activating the Nrf2/HO-1 pathway

Fig. 7

ML385 inhibit the effect of BML-111 on the H2O2-induced osteogenic dysfunction in hPDLFs. (A) Macroscopic and Microscopic images of ALP Staining and Alizarin Red Staining. (B) The ALP and ARS staining quantification of hPDLFs was shown. (C) The ALP, RUNX-2, OCN mRNA relative expression was shown. (D) Representative Western blots for ALP, RUNX-2, OCN protein. (E) The ALP, RUNX-2, OCN protein relative expression was shown. **P < 0.01 compared with control group. ##P < 0.01 compared with H2O2 group. &&P < 0.01 compared with H2O2 + BML-111 group. nsP>0.05 compared with control group. #P < 0.05 compared with H2O2 group. &P < 0.05 compared with H2O2 + BML-111 group. nsP>0.05 compared with BML-111 + H2O2 group

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BMC Oral Health

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