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Table 2 PR (95%CI) for PFAS and periodontitis risk in the NHANES from 2009–2014 (N = 3248)

From: Association of per- and polyfluoroalkyl substances (PFAS) with periodontitis: the mediating role of sex hormones

Categories

Unadjusted model

Adjusted model

PR (95%CI)

P value

PR (95%CI)

P value

PFOA [tertile (ng/mL)]

    

 Low (<1.87)

Ref

Ref

Ref

Ref

 Middle (1.87–3.17)

1.00(0.84,1.19)

0.998

0.96(0.87,1.06)

0.429

 High (≥ 3.17)

0.95(0.76,1.20)

0.685

0.97(0.86,1.08)

0.546

PFOS [tertile (ng/mL)]

    

 Low (<5.40)

Ref

Ref

Ref

Ref

 Middle (5.40–10.90)

1.07(0.81,1.41)

0.646

1.05(0.89,1.24)

0.569

 High (≥ 10.90)

1.47(1.13,1.91)

0.005

1.19(1.01,1.39)

0.033

PFHxS [tertile (ng/mL)]

    

 Low (<1.00)

Ref

Ref

Ref

Ref

 Middle (1.00-2.07)

1.22(1.02,1.46)

0.031

1.00(0.90,1.11)

0.995

 High (≥ 2.07)

1.12(0.88,1.43)

0.346

0.92(0.80,1.06)

0.259

MPAH [tertile (ng/mL)]

    

 Low (<0.07)

Ref

Ref

Ref

Ref

 Middle (0.07–0.20)

0.97(0.79,1.20)

0.771

0.96(0.85,1.08)

0.499

 High (≥ 0.20)

1.25(0.99,1.58)

0.061

1.09(0.95,1.25)

0.199

PFUA [tertile (ng/mL)]

    

 Low (<0.07)

Ref

Ref

Ref

Ref

 Middle (0.07–0.20)

0.93(0.71,1.23)

0.620

1.02(0.87,1.19)

0.829

 High (≥ 0.20)

1.12(0.85,1.48)

0.417

1.15(0.99,1.33)

0.060

PFNA [tertile (ng/mL)]

    

 Low (<0.74)

Ref

Ref

Ref

Ref

 Middle (0.74–1.30)

1.14(0.92,1.42)

0.220

1.05(0.92,1.19)

0.459

 High (≥ 1.30)

1.36(1.05,1.77)

0.022

1.17(1.02,1.34)

0.024

PFDE [tertile (ng/mL)]

    

 Low (<0.20)

Ref

Ref

Ref

Ref

 Middle (0.20–0.30)

1.06(0.84,1.35)

0.608

1.08(0.93,1.24)

0.310

 High (≥ 0.30)

1.07(0.81,1.40)

0.634

1.08(0.94,1.24)

0.287

  1. Note: Ref = Reference. Adjusted by age, sex, race/ethnicity, educational attainment, marital status, BMI, smoking status, alcohol intake, milk product consumption, poverty income ratio, and serum cotinine