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Table 5 Interproximal percent gingival bleeding sites at Baseline, Weeks 4 and 12

From: Efficacy of flossing and mouth rinsing regimens on plaque and gingivitis: a randomized clinical trial

Group

B

BA

BZ

BF

BFZ

Baseline

     

n

53

51

52

50

52

Mean

25.0

24.6

29.0

26.7

24.9

(SD)

12.03

12.66

13.20

10.77

11.31

Week 4

     

N

53

51

52

50

52

LSmean (SE)

18.4 (0.78)

5.2 (0.80)

5.5 (0.79)

12.1 (0.80)

4.1 (0.79)

Treatment groups versus B

     

p-value

 

< 0.001

< 0.001

< 0.001

< 0.001

Difference (SE)

 

-13.1 (1.11)

-12.8 (1.11)

-6.3 (1.12)

-14.3 (1.11)

95% CI

 

[-15.3, -10.9]

[-15.0, -10.6]

[-8.5, -4.1]

[-16.5, -12.1]

% reduction

 

71.6

69.8

34.1

77.9

Brush/Rinse groups versus BF Superiority

     

p-value

Difference (SE)

95% CI

% reduction

 

< 0.001

-6.9 (1.13)

[-9.1, -4.7]

56.8

< 0.001

-6.5 (1.12)

[-8.8, -4.3]

54.1

  

BFZ versus BF Superiority

     

p-value

Difference (SE)

95% CI

% reduction

    

< 0.001

-8.0 (1.12)

[-10.2, -5.8]

66.5

BFZ Rinse group versus BZ

     

p-value

Difference (SE)

95% CI

% reduction

    

0.184

-1.5 (1.12)

[-3.7, 0.7]

26.9

Week 12

     

n

52

50

52

50

50

LSmean (SE)

20.2 (0.97)

6.6 (0.99)

5.7 (0.97)

15.1 (0.99)

4.4 (0.99)

Treatment groups versus B

     

p-value*

 

< 0.001

< 0.001

< 0.001

< 0.001

Difference (SE)

 

-13.5 (1.38)

-14.4 (1.38)

-5.1 (1.38)

-15.8 (1.38)

95% CI

 

[-16.2, -10.8]

[-17.1, -11.7]

[-7.8, -2.4]

[-18.5, -13.1]

% reduction

 

67.0

71.5

25.2

78.4

Brush/Rinse groups versus BF Superiority

     

p-value

Difference (SE)

95% CI

% reduction

 

< 0.001

-8.4 (1.40)

[-11.2, -5.7]

55.9

< 0.001

-9.3 (1.39)

[-12.1, -6.6]

61.9

  

BFZ versus BF Superiority

     

p-value

Difference (SE)

97.5% CI

% reduction

    

< 0.001

-10.7 (1.40)

[-13.5, -8.0]

71.0

BFZ versus BZ Superiority

     

p-value

Difference (SE)

95% CI

% reduction

    

0.321

-1.4 (1.39)

[-4.1, 1.4]

24.1

  1. B Brush Only, BA Brush/Rinse (EO alcohol-containing mouthrinse), BF Brush/Floss, BFZ Brush/Floss/Rinse (EO non-alcohol containing mouthrinse), BZ Brush/Rinse (EO non-alcohol containing mouthrinse), CI confidence interval, LSmean least square means, SD standard deviation, SE standard error
  2. All p-values, model-based estimated means (LSmeans), and standard errors were based on a mixed effects model for repeated measures analysis (MMRM), with the fixed effects including treatment, visit, and treatment by visit interaction; baseline as a covariate; and baseline by visit interaction