Table 6 Whole mouth, interproximal mean probing depth and bleeding on probing (BOP), Week 12

Whole Mouth Mean Probing Depth

Baseline

n

53

51

52

50

52

Mean

2.05

2.00

2.12

2.05

2.07

(SD)

0.319

0.329

0.395

0.307

0.334

Week 12

N

52

50

52

50

50

LSmean (SE)

2.02 (0.036)

1.62 (0.037)

1.64 (0.036)

1.61 (0.037)

1.57 (0.037)

Treatment groups versus B

p-value

< 0.001

< 0.001

< 0.001

< 0.001

Difference (SE)

-0.40 (0.051)

-0.38 (0.051)

-0.41 (0.051)

-0.44 (0.051)

95% CI

[-0.50, -0.30]

[-0.48, -0.28]

[-0.51, -0.31]

[-0.54, -0.34]

% reduction

19.9

18.7

20.3

22.0

Brush/Rinse groups versus BF

p-value

Difference (SE)

95% CI

% reduction

0.869

0.01 (0.052)

[-0.09, 0.11]

-0.5

0.541

0.03 (0.051)

[-0.07, 0.13]

-2.0

BFZ versus BF

p-value

Difference (SE)

95% CI

% reduction

0.512

-0.03 (0.052)

[-0.14, 0.07]

2.1

BFZ versus BZ

p-value

Difference (SE)

95% CI

% reduction

0.203

-0.07 (0.051)

[-0.17, 0.04]

4.0

Whole Mouth Mean BOP

Baseline

n

53

51

52

50

52

Mean

0.099

0.099

0.144

0.087

0.106

(SD)

0.1303

0.1152

0.1840

0.1143

0.1224

Week 12

n

52

50

52

50

50

LSmean (SE)

0.045 (0.0080)

0.034 (0.0082)

0.045 (0.0081)

0.020 (0.0082)

0.027 (0.0082)

Treatment groups versus B

p-value

0.343

0.967

0.028

0.120

Difference (SE)

-0.011 (0.0114)

-0.000 (0.0114)

-0.025 (0.0115)

-0.018 (0.0114)

95% CI

[-0.033, 0.012]

[-0.023, 0.022]

[-0.048, -0.003]

[-0.040, 0.005]

% reduction

24.0

1.1

55.7

39.4

Brush/Rinse groups versus BF

p-value

Difference (SE)

95% CI

% reduction

0.215

0.014 (0.0116)

[-0.008, 0.037]

-71.7

0.033

0.025 (0.0115)

[0.002, 0.048]

-123.5

BFZ versus BF

p-value

Difference (SE)

95% CI

% reduction

0.524

0.007 (0.0116)

[-0.015, 0.030]

-36.8

BFZ versus BZ

p-value

Difference (SE)

95% CI

% reduction

0.132

-0.017 (0.0115)

[-0.040, 0.005]

38.8

Interproximal Mean Probing Depth

Baseline

n

53

51

52

50

52

Mean

2.31

2.24

2.39

2.29

2.31

(SD)

0.328

0.344

0.404

0.312

0.340

Week 12

n

52

50

52

50

50

LSmean (SE)

2.27 (0.041)

1.83 (0.042)

1.85 (0.041)

1.84 (0.042)

1.78 (0.042)

Treatment groups versus B

p-value

< 0.001

< 0.001

< 0.001

< 0.001

Difference (SE)

-0.44 (0.059)

-0.42 (0.058)

-0.44 (0.059)

-0.49 (0.059)

95% CI

[-0.56, -0.33]

[-0.54, -0.31]

[-0.55, -0.32]

[-0.61, -0.38]

% reduction

19.4

18.6

19.3

21.7

Brush/Rinse groups versus BF

p-value

Difference (SE)

95% CI

% reduction

0.950

-0.00 (0.059)

[-0.12, 0.11]

0.2

0.803

0.02 (0.059)

[-0.10, 0.13]

-0.8

BFZ versus BF

p-value

Difference (SE)

95% CI

% reduction

0.348

-0.06 (0.059)

[-0.17, 0.06]

3.0

BFZ versus BZ

p-value

Difference (SE)

95% CI

% reduction

0.232

-0.07 (0.059)

[-0.19, 0.05]

3.8

Interproximal Mean BOP

Baseline

n

53

51

52

50

52

Mean

0.109

0.104

0.156

0.099

0.113

(SD)

0.1519

0.1244

0.1990

0.1270

0.1304

Week 12

n

52

50

52

50

50

LSmean (SE)

0.051 (0.0095)

0.039 (0.0097)

0.052 (0.0095)

0.019 (0.0097)

0.030 (0.0096)

Treatment groups versus B

p-value

0.414

0.911

0.022

0.131

Difference (SE)

-0.011 (0.0135)

0.002 (0.0134)

-0.031 (0.0135)

-0.020 (0.0135)

95% CI

[-0.038, 0.016]

[-0.025, 0.028]

[-0.058, -0.005]

[-0.047, 0.006]

% reduction

21.9

-3.0

61.7

40.5

Brush/Rinse groups versus BF

p-value

Difference (SE)

95% CI

% reduction

0.141

0.020 (0.0136)

[-0.007, 0.047]

-104.2

0.017

0.033 (0.0136)

[0.006, 0.060]

-169.2

BFZ versus BF

p-value

Difference (SE)

95% CI

% reduction

0.433

0.011 (0.0137)

[-0.016, 0.038]

-55.5

BFZ versus BZ

p-value

Difference (SE)

95% CI

% reduction

0.107

-0.022 (0.0136)

[-0.049, 0.005]

42.2