Table 7 Whole mouth mean Turesky Plaque Index (TPI) at Baseline, Weeks 4, 12

Baseline

n

53

51

52

50

52

Mean

3.07

2.98

3.00

3.13

3.03

(SD)

0.402

0.468

0.364

0.407

0.432

Week 4

N

53

51

52

50

52

Lsmean (SE)

2.91 (0.046)

1.98 (0.047)

2.26 (0.046)

2.86 (0.047)

2.29 (0.046)

Treatment groups versus B

p-value

< 0.001

< 0.001

0.430

< 0.001

Difference (SE)

-0.93 (0.065)

-0.65 (0.065)

-0.05 (0.066)

-0.63 (0.065)

95% CI

[-1.06, -0.80]

[-0.78, -0.52]

[-0.18, 0.08]

[-0.76, -0.50]

% reduction

32.0

22.4

1.80

21.5

Brush/Rinse groups versus BF Superiority

p-value

< 0.001

< 0.001

Difference (SE)

-0.88 (0.067)

-0.60 (0.066)

95% CI

[-1.01, -0.75]

[-0.73, -0.47]

% reduction

30.8

21.0

BFZ versus BF Superiority

p-value

< 0.001

Difference (SE)

-0.58 (0.066)

95% CI

[-0.71, -0.45]

% reduction

20.1

BFZ versus BZ

p-value

0.695

Difference (SE)

0.03 (0.065)

95% CI

[-0.10, 0.15]

% reduction

-1.1

Week 12

N

52

50

52

50

50

Lsmean (SE)

2.82 (0.045)

1.80 (0.046)

2.14 (0.045)

2.89 (0.046)

2.21 (0.046)

Treatment groups versus B

p-value

< 0.001

< 0.001

0.229

< 0.001

Difference (SE)

-1.01 (0.064)

-0.67 (0.064)

0.08 (0.064)

-0.61 (0.064)

95% CI

[-1.14, -0.88]

[-0.80, -0.55]

[-0.05, 0.20]

[-0.73, -0.48]

% reduction

35.9

23.9

-2.8

21.6

Brush/Rinse groups versus BF Superiority

p-value

< 0.001

< 0.001

Difference

-1.09 (0.065)

-0.75 (0.065)

95% CI

[-1.22, -0.96]

[-0.88, -0.62]

% reduction

37.6

25.9

BFZ versus BF Superiority

p-value

< 0.001

Difference (SE)

-0.69 (0.065)

95% CI

[-0.81, -0.56]

% reduction

23.7

BFZ versus BZ Superiority

p-value

0.318

Difference (SE)

0.06 (0.064)

95% CI

[-0.06, 0.19]

% reduction

-3.0