Table 8 Whole mouth mean Modified Gingival Index (MGI) at Baseline, Weeks 4, 12

Baseline

n

53

51

52

50

52

Mean

2.56

2.56

2.65

2.58

2.63

(SD)

0.307

0.320

0.288

0.270

0.261

Week 4

N

53

51

52

50

52

LSmean (SE)

2.58 (0.050)

1.69 (0.051)

1.68 (0.050)

2.41 (0.051)

1.64 (0.050)

Treatment groups versus B

p-value

< 0.001

< 0.001

0.016

< 0.001

Difference (SE)

-0.89 (0.071)

-0.90 (0.071)

-0.17 (0.071)

-0.94 (0.071)

95% CI

[-1.03, -0.75]

[-1.04, -0.76]

[-0.31, -0.03]

[-1.08, -0.80]

% reduction

34.4

35.0

6.7

36.3

Brush/Rinse groups versus BF Superiority

p-value

< 0.001

< 0.001

Difference (SE)

-0.72 (0.072)

-0.73 (0.072)

95% CI

[-0.86, -0.57]

[-0.87, -0.59]

% reduction

29.7

30.3

BFZ group versus BF Superiority

p-value

< 0.001

Difference (SE)

-0.77 (0.072)

95% CI

[-0.91, -0.62]

% reduction

31.8

BFZ versus BZ

p-value

0.626

Difference (SE)

-0.03 (0.071)

95% CI

[-0.17, 0.10]

% reduction

2.10

Week 12

N

52

50

52

50

50

LSmean (SE)

2.52 (0.054)

1.37 (0.055)

1.43 (0.054)

2.38 (0.055)

1.47 (0.055)

Treatment groups versus B

p-value

< 0.001

< 0.001

0.076

< 0.001

Difference

-1.15 (0.077)

-1.09 (0.076)

-0.14 (0.077)

-1.04 (0.077)

95% CI

[-1.30, -1.00]

[-1.24, -0.94]

[-0.29, 0.01]

[-1.19, -0.89]

% reduction

45.7

43.3

5.4

41.5

Brush/Rinse groups versus BF Superiority

p-value

< 0.001

< 0.001

Difference (SE)

-1.01 (0.077)

-0.95 (0.077)

95% CI

[-1.17, -0.86]

[-1.11, -0.80]

% reduction

42.6

40.1

BFZ versus BF Superiority

p-value

< 0.001

Difference (SE)

-0.91 (0.077)

95% CI

[-1.06, -0.76]

% reduction

38.1

BFZ versus BZ Superiority

p-value

0.541

Difference (SE)

0.05 (0.077)

95% CI

[-0.10, 0.20]

% reduction

-3.3