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Table 1 Demographic and clinical information of the study patients

From: Can medication-related osteonecrosis of the jaw be attributed to specific microorganisms through oral microbiota analyses? A preliminary study

Patient

Age/Sex

Underlying Disease(s)

Drug Type and Duration

Stage/Location

Trigger Factor

1

85/F

Hypertension, osteoporosis

PO, risedronate 2017–2021

II/Mn Rt

Extraction

2

83/F

Hypertension, diabetes, osteoporosis

PO, ibandronate

2010–2020;

SC, denosumab

2020–2021

II/Mn Rt

Extraction

3

81/F

Multiple myeloma

IV, zoledronic Acid 2020–2021

III/Mx Rt

Periodontitis

4

90/F

Osteoporosis

PO, ibandronate

2000–2010;

IV, ibandronate

2011–2021

II/Mn Rt

Extraction

5

83/F

Hypertension, osteoporosis

PO, ibandronate

2016–2019;

IV, ibandronate

2019 ~ 2021

II/Mx Rt

Extraction

6

80/F

Hypertension, diabetes, osteoporosis

PO, alendronate 2017–2022

II/Mn Rt

Implantation

7

88/F

Hypertension, osteoporosis

PO, alendronate 2016 ~ 2021

II/Mn Rt

Periodontitis

8

86/F

Hypertension, angina, osteoporosis

IV, pamidronate 2013–2022

II/Mn Lt

Extraction

9

87/F

Arrhythmia, osteoporosis

PO, ibandronate 2011–2013;

PO, risedronate 2013–2018;

PO, ibandronate 2019–2020;

SC, denosumab

2021–2022

II/Mn Lt

Extraction

10

72/F

Osteoporosis

IV, zoledronate 2017–2021

II/Mn Lt

Extraction

11

72/F

Osteoporosis

SC, denosumab

2020–2022

III/Mx Lt

Periodontitis

12

85/F

Osteoporosis

IV, pamidronate

2017–2021

III/Mn Rt

Extraction

  1. F female, IV intravenous, Lt left, M male, Mn mandible, Mx maxilla, PO per oral, Rt right, SC subcutaneous