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Table 2 Concentrations and total amounts of GCF LXA4 in the study groups before and after SRP

From: Lipoxin A4 levels predict site-specific clinical improvements post scaling and root planing and correlate negatively with periodontal pathogens in severe periodontitis

 

Healthy

(n = 64)

Severe periodontitis

(n = 74)

LXA4 concentrations

(pg/µl)

  

Baseline

251.46 ± 128.13

86.13 ± 60.81a

1 m

-

163.09 ± 159.45a,b

3 m

-

232.16 ± 317.86a,b

6 m

-

139.20 ± 107.11a,c

LXA4 total amounts

(pg/sample)

  

Baseline

59.38 ± 22.08

42.69 ± 22.85a

1 m

-

58.19 ± 30.20b

3 m

-

62.69 ± 37.22b

6 m

-

57.27 ± 31.27b

GCF volume

(µl)

  

Baseline

0.30 ± 0.13

0.56 ± 0.22a

1 m

-

0.49 ± 0.24a,b

3 m

-

0.44 ± 0.23a,b

6 m

-

0.53 ± 0.24a

  1. Two patients with periodontitis were unavailable for the 1month and 3 months follow-up respectively
  2. Abbreviations: m, month
  3. a, p < 0.05, compared with healthy controls at baseline;
  4. b, p < 0.05, compared with periodontitis group at baseline;
  5. c, p < 0.05, compared with periodontitis group at 3 months after SRP;