Table 3 The levels of LXA4 at different sites with varying degrees of PD reduction at different timepoints after SRP in patients with severe periodontitis were analyzed after adjusting for gender, age, and plaque accumulation
Concentrations (pg/µl) | ΔPD ≥ 2 mm at 1 m | ΔPD ≥ 2 mm at 3 m | ΔPD ≥ 2 mm at 6 m | ||||||
|---|---|---|---|---|---|---|---|---|---|
Yes (n = 52) | No (n = 18) | p | Yes (n = 52) | No (n = 14) | p | Yes (n = 59) | No (n = 15) | p | |
Baseline LXA4 | 82.53 ± 56.11 | 99.41 ± 75.45 | 0.251 | 77.91 ± 56.92 | 109.22 ± 77.53 | 0.017 | 79.51 ± 54.80 | 112.16 ± 77.00 | 0.018 |
LXA4 post-treatment | 172.59 ± 163.20 | 135.63 ± 149.03 | 0.408 | 248.30 ± 351.89 | 172.22 ± 120.36 | 0.497 | 148.80 ± 114.39 | 101.44 ± 60.72 | 0.189 |
Increase of LXA4 post-treatment | 90.06 ± 166.12 | 36.22 ± 103.75 | 0.148 | 170.40 ± 347.38 | 63.00 ± 115.82 | 0.294 | 69.29 ± 113.98 | -10.72 ± 70.84 | 0.017 |