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Fig. 2 | BMC Oral Health

Fig. 2

From: Temporal gene expression profiling during early-stage traumatic temporomandibular joint bony ankylosis in a sheep model

Fig. 2

Histological observation of temporomandibular joint intra-articular hematoma or newly generated ankylosed callus at each post-operation time point (haematoxylin and eosin stain: 10 × 200 μm, 20 × 100 μm and 40 × 50 μm). Day 1: Blood clots containing a large number of neutrophils filled the articular space. Day 4: The apparent inflammatory cells subsided, and fibroblasts appeared for the first time. Day 7: The inflammatory cells disappeared completely, and organisation of the blood clots commenced, with cell transformations in a fibrovascular structure with small vessels and an immature collagenous network. Day 9 & Day 11: fibroblasts and a large number of red-stained collagen bundles were observed. Day 14 & Day 28: Cartilage formed locally and was characterised by fibrocartilage

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