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Table 4 Studies with unacceptable high risk of confounding bias

From: Does smoking cessation affect postoperative healing following oral surgery among smokers? – a systematic review

Author, year, country

Study design

Study population

Intervention

Control

Outcome

Comment

Bain, 1996, Scotland [15]

Prospective longitudinal study

Patients receiving dental implants

Smoking cessation

No smoking or smoking

Implant failure

Not handling confounding factors

Mundt et al, 2006, Germany [17]

Retrospective cohort study

Patients receiving dental implants

Former smoker

Current smoker

Implant failure

Not handling confounding factors, in relation to our research question

Levin et al, 2004, Israel [16]

Retrospective cohort study

Patients receiving onlay bone grafts or sinus lifts

Former smoker

No-smoking

Complications after surgery

Not handling confounding factors