Skip to main content
Fig. 1 | BMC Oral Health

Fig. 1

From: Causal relationship between hypothyroidism and temporomandibular disorders: evidence from complementary genetic methods

Fig. 1

Overview of the present MR study. (A) Univariable MR analyses to estimate overall effects between thyroid health (hypothyroidism; hyperthyroidism; thyroid-stimulating hormone, TSH; free thyroxine, fT4) and temporomandibular disorders (TMDs); (B) Multivariable MR analyses to estimate direct effects of hypothyroidism of TMDs; (C) Applying the same multivariable framework to estimate the indirect effects on TMDs mediated along the causal pathway via TSH, fT4 or hyperthyroidism. The colored arrows in red and green on these graphs illustrate the causal effect of hypothyroidism on the outcome being estimated in multivariable MR analyses

Back to article page

BMC Oral Health

ISSN: 1472-6831

Contact us