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Fig. 4 | BMC Oral Health

Fig. 4

From: Causal relationship between hypothyroidism and temporomandibular disorders: evidence from complementary genetic methods

Fig. 4

Multivariable MR estimating the association of thyroid-stimulating hormone, free thyroxine, hypothyroidism, and hyperthyroidism with temporomandibular disorders. Red plots represent the multivariable MR analyses of the effects of hypothyroidism on temporomandibular disorders (TMDs) after adjusting for hyperthyroidism, thyroid-stimulating hormone (TSH), and free thyroxine (fT4); Green plots represent the multivariable MR analyses of the effects of hyperthyroidism on TMDs after adjusting for hypothyroidism, TSH, and fT4; Blue plots represent the multivariable MR analyses of the effects of the effects of fT4 on TMDs after adjusting for hypothyroidism, TSH, and hyperthyroidism; Yellow plots represent the multivariable MR analyses of the effects of the effects of TSH on TMDs after adjusting for hypothyroidism, fT4, and hyperthyroidism; Abbreviations: N. SNPs, number of SNPs used in MR; OR, odds ratio; CI, confidence intervals; IVW, inverse variance weighted

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