Table 4 GSTs genotype frequencies in periodontitis patients and controls
Genotypes | Controls (N = 204) | Periodontitis patients (N = 203) | p level | OR (95%CI) |
|---|---|---|---|---|
GSTM1 | Â | Â | Â | Â |
Wild | 100 (49.0) | 97 (47.8) | 0.44 | 1.00 |
Null | 104 (51.0) | 106 (52.2) | 1.05 (0.71–1.55) | |
GSTT1 | Â | Â | Â | Â |
Wild | 152 (74.5) | 166 (81.8) | 0.05* | 1.00 |
Null | 52 (25.5) | 37 (18.2) | 0.65 (0.40–1.05) | |
GSTM1/GSTT1 | Â | Â | Â | Â |
Both wild | 71 (34.8) | 78 (38.4) | 0.61 | 1.00 |
Either null | 110 (53.9) | 107 (52.7) | 0.89 (0.58–1.34) | |
Both null | 23 (11.3) | 18 (8.9) | 0.71 (0.36–1.43) | |
GSTP1 Ile105Val (rs1695, A313G)# | Â | |||
AA (Ile/Ile) | 75 (50.0) | 108 (54.0) | 0.55 | 1.00 |
AG (Ile/Val) | 66 (44.0) | 77 (38.5) | 0.81 (0.52–1.26) | |
GG (Val/Val) | 9 (6.0) | 15 (7.5) | 1.16 (0.48–2.78) | |
GSTP1 Ala114Val (rs1138272, C341T) # | Â | |||
CC (Ala/Ala) | 126 (84.0) | 178 (89.0) | 0.02* | 1.00 |
CT (Ala/Val) | 24 (16.0) | 17 (8.5) | 0.50 (0.26–0.97) | |
TT (Val/Val) | 0 (0.0) | 5 (2.5) | NA | |
GSTP1# | Â | Â | Â | Â |
*A/*A | 75 (36.8) | 108 (53.2) | 0.10 | 1.00 |
*A/*B | 47 (23.0) | 62 (30.5) | 1.09 (0.68–1.76) | |
*A/*C | 19 (9.3) | 15 (7.4) | 0.55 (0.26–1.15) | |
*B/*B | 4 (2.0) | 8 (3.9) | 1.39 (0.40–4.78) | |
*B/*C | 5 (2.4) | 2 (1.0) | 0.28 (0.05–1.47) | |
*C/*C | 0 (0.0) | 5 (2.5) | NA | |