Table 2 Knowledge, perception and treatment options of MIH. Univariate analysis between DS (Dental students) and DHS (Dental Hygiene students). Multivariate analysis for Gender (female/male), type of center (center of study public/private) and Group of studies.

Q5

Have you heard of Molar Incisor Hypomineralization (MIH)?

-Yes

130 (97%)

88 (56.4%)

< 0.001*

0.513

0.005*

0.000*

Q6

Through what source/s have you heard about MIH?

-Scientific publications

55 (41%)

22 (14.1%)

< 0.001*

0.495

0.258

0.000*

-Master classes

103 (76.9%)

45 (28.8%)

< 0.001*

0.239

0.002*

0.000*

-Conferences and/or courses

33 (24.6%)

10 (6.4%)

< 0.001*

0.272

0.268

0.001*

-Information brochures

7 (5.2%)

4 (2.6%)

0.237

0.394

0.226

0.280

-Internet

52 (38.8%)

37 (23.7%)

0.005*

0.567

0.445

0.006*

-Textbooks

49 (36.6%)

23 (14.7%)

< 0.001*

0.505

0.693

0.000*

-Clinical practice

93 (69.4%)

22 (14.1%)

< 0.001*

0.773

0.760

0.000*

-Others

38 (28.4%)

26 (16.7%)

0.017*

0.217

0.872

0.083

Q7

Do you know the clinical features of MIH?

-Yes

127 (94.8%)

73 (46.8%)

< 0.001*

0.114

0.026*

0.000*

Q8

Which teeth do you think are most frequently affected?

-Permanent first molars and permanent incisors

106 (79.1%)

81 (51.9%)

< 0.001*

0.762

0.564

0.000*

-Permanent first molars and incisors and temporary second molars

25 (18.7%)

37 (23.7%)

0.295

0.511

0.002*

0.106

-I do not know/not sure

4 (3%)

43 (27.6%)

< 0.001*

0.112

0.010*

0.000*

Q9

Do you have difficulty distinguishing the MIH lesion from other lesions or malformations of dental tissues?

-Yes

64 (47.8%)

102 (65.4%)

0.002*

0.617

0.120

0.005*

Q10

With which ones do you have difficulty distinguishing MIH?

-Dental fluorosis

21 (15.7%)

34 (20.7%)

0.185

0.243

0.829

0.313

-Enamel hypoplasia

66 (49.3%)

43 (27.6%)

< 0.001*

0.885

0.483

0.000*

-Amelogenesis imperfecta

39 (29.1%)

27 (17.3%)

0.017*

0.526

0.855

0.072

-Dentinogenesis imperfecta

13 (9.7%)

13 (8.3%)

0.684

0.690

0.378

0.851

-Caries

15 (11.2%)

4 (2.6%)

0.003*

0.924

0.233

0.020*

-Other

3 (2.2%)

24 (15.4%)

< 0.001*

0.421

0.487

0.010*

Q11

What factors do you think are involved in the etiology of MIH?

-Genetic factors

98 (73.1%)

99 (63.5%)

0.078

0.181

0.689

0.166

-Chronic diseases of the mother during pregnancy

61 (45.5%)

34 (21.8%)

< 0.001*

0.076

0.855

0.000*

-Chronic diseases in the child

42 (31.3%)

30 (19.2%)

0.017*

0.115

0.060

0.001*

-Antibiotics/drugs taken by the mother during pregnancy

52 (38.8%)

40 (25.6%)

0.016*

0.467

0.282

0.047*

- Antibiotics/drugs taken by the child

27 (20.1%)

23 (14.7%)

0.224

0.490

0.890

0.074

-Environmental pollutants

34 (25.4%)

15 (9.6%)

0.001*

0.178

0.037*

0.005*

-Acute illnesses affecting the mother during pregnancy

64 (47.8%)

31 (19.9%)

< 0.001*

0.587

0.479

0.000*

- Acute illnesses affecting the child

45 (33.6%)

17 (10.9%)

< 0.001*

0.199

0.985

0.000*

-Exposure to fluoride

8 (6%)

26 (16.7%)

0.005*

0.725

0.209

0.047*

-None

2 (1.5%)

2 (1.3%)

0.878

0.998

0.288

0.837

-Other

5 (3.7%)

21 (13.5%)

0.004*

0.815

0.908

0.015*

Q12

What do you think is the prevalence of MIH in Spain?

< 5%

9 (6.7%)

7 (4.5%)

0.407

0.016*

0.426

0.792

5–10%

39 (29.1%)

38 (24.4%)

0.362

0.039*

0.394

0.043*

10–20%

37 (27.6%)

32 (20.5%)

0.157

0.212

0.001*

0.347

> 20%

18 (13.4%)

4 (2.6%)

< 0.001*

0.632

0.887

0.002*

Not sure

36 (26.9%)

73 (46.8%)

< 0.001*

0.413

0.067

0.007*

Q13

Do you think the pattern of caries in teeth with MIH is different from the pattern of normal caries?

Yes

105 (78.4%)

83 (53.2%)

< 0.001*

0.636

0.072

0.000*

No

22 (16.4%)

18 (11.5%)

0.230

0.286

0.823

0.030*

Not sure

7 (5.2%)

52 (33.3%)

< 0.001*

0.486

0.171

0.000*

Q14

How confident do you feel about diagnosing a tooth with MIH?

-Confident

84 (62.7%)

37 (23.7%)

< 0.001*

0.228

0.449

0.000*

Q15

Would you like to receive more training on MIH in your career/training content?

Yes

111 (82.8%)

132 (84.6%)

0.682

0.746

0.269

0.944

Q16

On what aspects of MIH do you think you need to complete your training?

-Diagnosis

72 (53.7%)

93 (59.6%)

0.313

0.906

0.492

0.299

-Etiology

44 (32.8%)

81 (51.9%)

0.001*

0.964

0.689

0.020*

-Treatment

83 (61.9%)

83 (53.2%)

0.134

0.408

0.846

0.635

Others: prevention, long-term prognosis, etc.

61 (45.5%)

90 (57.7%)

0.039*

0.910

0.833

0.081

TREATMENT OPTIONS

NONOPERATIVE AND OPERATIVE

Q17

What preventive (nonoperative) treatment would you apply to MIH lesions without enamel fracture?

-Dental mousse with Recaldent

16 (11.9%)

19 (12.2%)

0.950

0.910

0.052

0.471

-Dental mousse with Recaldent and fluoride

72(53.7%)

24 (15.4%)

< 0.001*

0.172

0.968

0.000*

-Professional application of high concentration fluoride varnish (22.600 ppm)

94 (70.1%)

47 (30.1%)

< 0.001*

0.492

0.152

0.000*

-Professional application of chlorhexidine varnish.

3 (2.2%)

12 (7.7%)

0.037*

0.620

0.363

0.994

-Sealing of pits and fissures.

49 (36.6%)

36 (23.1%)

0.012*

0.711

0.792

0.008*

-Application of silver diamine fluoride.

10 (7.5%)

9 (5.8%)

0.561

0.093

0.036*

0.970

-Others.

3 (2.2%)

18 (11.5%)

0.002*

0.261

0.295

0.149

Q18

What operative treatment would you apply to teeth affected by MIH with enamel fracture?

-Microabrasion

8 (6%)

11 (7.1%)

0.711

0.629

0.354

0.372

-Resin infiltration.

0 (0%)

1 (0.6%)

0.353

--

--

--

-Conventional glass ionomer

33 (24.6%)

31 (19.9%)

0.330

0.790

0.107

0.086

-Resin-modified glass ionomer

63 (47%)

74 (47.4%)

0.943

0.543

0.669

0.750

-Composite filling

66 (49.3%)

70 (44.9%)

0.456

0.568

0.011*

0.032*

-Silver amalgam filling

1 (0.7%)

3 (1.9%)

0.392

--

--

--

-Preformed crowns

37 (27.6%)

45 (28.8%)

0.816

0.810

0.112

0.026*

-Extraction

8 (6%)

5 (3.2%)

0.257

0.904

0.228

0.236