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Fig. 3 | BMC Oral Health

Fig. 3

From: Inhibition of ZDHHC16 promoted osteogenic differentiation and reduced ferroptosis of dental pulp stem cells by CREB

Fig. 3

The inhibition of ZDHHC16 reduced Ferroptosis of DPSCs

GPX4 protein expression (A1, A2), GSH activity (C), MPT (calcein AM/CoCl2 assay, G), JC-1 disaggregation (H) were inhibited by up-regulation of ZDHHC16, and iron concentration (D), LDH activity level (E), PI positive cells (F) were increased by up-regulation of ZDHHC16; GPX4 protein expression (B1, B2), GSH activity (C), MPT (calcein AM/CoCl2 assay, G), JC-1 disaggregation (H) were increased by down-regulation of ZDHHC16, and iron concentration (D), LDH activity level (E), PI positive cells (F) were decreased by down-regulation of ZDHHC16.

**p < 0.01 compared with negative or si-nc.

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BMC Oral Health

ISSN: 1472-6831

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