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Fig. 6 | BMC Oral Health

Fig. 6

From: Inhibition of ZDHHC16 promoted osteogenic differentiation and reduced ferroptosis of dental pulp stem cells by CREB

Fig. 6

CREB regulated the effects of ZDHHC16 on Osteogenic differentiation of DPSCs

CREB agonist promoted OD of DPSCs by ZDHHC16 up-regulation: ALP mRNA expression and staining (×50, A1,A2), Col1a1 (B), OCN (C), OSX (D) and Runx2 mRNA expression(E); CREB inhibitor reduced OD of DPSCs by down-regulation of ZDHHC16: ALP mRNA expression and staining (×50, F1, F2), Col1a1 (G), OCN (H), OSX (I) and Runx2 (J) in DPSCs by ZDHHC16 down-regulation.

**p < 0.01 compared with negative or si-nc, ##p < 0.01 compared with ZDHHC16 or si-ZDHHC16.

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BMC Oral Health

ISSN: 1472-6831

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