Fig. 1From: Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic ratsExperimental protocol. T2DM rats were intraperitoneally injected by STZ at 4 weeks after HFD. Tooth extraction surgery was performed at 5 weeks after HFD. Different concentrations of ART-loaded TCH were immediately injected into the socket after tooth extraction in a single injection. Finally, rats were sacrificed at 2 months post tooth extraction. T2DM, type 2 diabetes mellitus group; TCH, thermosensitive chitosan hydrogel group; Low, 50Â mg/ml ART-loaded TCH group; Medium, 100Â mg/ml ART-loaded TCH group; High; 150Â mg/ml ART-loaded TCH groupBack to article page