NHANES-based analysis of the correlation between leisure-time physical activity, serum cotinine levels and periodontitis risk

Table 3 Interaction between amateur physical activity and serum cotinine levels on the risk of periodontitis

Variant	Model 1		Model 2
Variant	OR (95% CI)	P	OR (95% CI)	P
Serum cotinine levels < 0.05 ng/ml & Lots of leisure time sports activities	Ref		Ref
Serum cotinine level < 0.05ng/ml & Low leisure time physical activity	1.70 (1.38–2.09)	< 0.001	1.20 (0.94–1.53)	0.135
Serum cotinine level ≥ 0.05ng/ml & Lots of leisure time sports activities	1.70 (1.21–2.37)	0.003	1.38 (0.94–2.03)	0.101
Serum cotinine level ≥ 0.05 ng/ml & Low leisure time physical activity	3.66 (2.90–4.61)	< 0.001	2.48 (1.88–3.27)	< 0.001
RERI (95% CI)	1.29 (0.77–1.81)		0.90 (0.44–1.36)
API (95% CI)	0.35 (0.22–0.48)		0.36 (0.18–0.55)
SI (95% CI)	1.94 (1.34–2.80)		2.55 (1.03–6.28)

OR: prevalence; CI: confidence interval; Ref: reference value; RERI: relative excess risk due to interaction; API: attributable proportion of interaction; SI: synergy index: attributable proportion of interaction; SI: synergy index
Model 1: Unadjusted univariate logistic regression model
Model 2: Multivariate Logistic Regression Model Adjusting for Age, Gender, Race, Marital Status, PIR, Screen Time, Diabetes, Hypertension, Dyslipidemia, Cardiovascular Disease, NSAIDs, VD, Flossing/Dental Appliances, Total Energy, and MED Score

ISSN: 1472-6831