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Table 7 Assessment of certainty of evidence of the evaluation of the association between malocclusion and dental age (GRADE)

From: Association between dental age and malocclusions: a systematic review

Certainty assessment

Participants

(studies)

Follow-up

Risk of bias

Inconsistency

Indirectness

Imprecision

Publication bias

Overall certainty of evidence

Sagittal discrepancies

 647

(4 observational studies) 

seriousa

seriousb

not serious

not serious

none

Very low

Vertical discrepancies

 784

(6 observational studies)

seriousa

not serious

not serious

not serious

none

Very low

Transversal discrepancy

 101

(1 observational study)

seriousc

not serious

not serious

seriousd

none

Very low

  1. aMost of the studies included presented a moderate quality
  2. bThe studies included presented different directions of effect
  3. cThe study presented a moderate quality
  4. dThe optimal information size (≥400) was not attended