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Fig. 2 | BMC Oral Health

Fig. 2

From: Challenging pitfalls in frozen section pathology: a case of mandible ghost cell odontogenic carcinoma and the literature review

Fig. 2

Postoperative pathology analysis. (A, B) Gross excision specimen and tumor incision surface (red circles). (C) Microscopically, paraffin section showed the tumor boundary was not clear. (D, E) Hematoxylin and eosin stain (HE) showed that tumor cells are arranged in solid nests and anastomosing cords. (F, G) The tumor was composed of small cells with hyperchromatic nuclei or large cells with vacuolated nuclei, with marked heterogeneity and mitotic activity (red arrows). (H, I) A calcified cystic tumor component of odontogenic origin could be seen and the malignant epithelial component were separated from or mixed with the benign lesion. (J-O) Ghost cells (J), dentinoid material (K), hemorrhage (L), necrosis (M) and calcifications (N) could be found, with foreign body reaction around ghost cell (O).

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