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Table 2 Patient-related clinical measures for 30 smokers compared with 30 non-smokers at T0, T1 and T2

From: Serum biomarker levels in smokers and non-smokers following periodontal therapy. A prospective cohort study

 

T0

P

T1

P

T2

p

ΔT0−T1

p

ΔT1−T2

p

ΔT0−T2

p

PD

      

Mean diff ± SEM

 

Mean diff ± SEM

 

Mean diff ± SEM

 

Non-smokers

3.34 ± 0.08

 

2.31 ± 0.06

 

2.43 ± 0.06

 

1.02 ± 0.06

< 0.001

-0.12 ± 0.05

0.026

0.91 ± 0.06

< 0.001

Smokers

3.71 ± 0.08

 

2.65 ± 0.69

 

2.81 ± 0.08

 

1.06 ± 0.07

< 0.001

-0.16 ± 0.67

0.019

0.90 ± 0.71

< 0.001

Mean diff ± SEM

0.38 ± 0.11

0.001

0.34 ± 0.09

< 0.001

0.39 ± 0.11

0.001

0.04 ± 0.93

0.995

-0.05 ± 0.82

0.910

-0.01 ± 0.09

0.833

CAL

      

Mean diff ± SEM

 

Mean diff ± SEM

 

Mean diff ± SEM

 

Non-smokers

3.95 ± 0.09

 

3.10 ± 0.08

 

3.17 ± 0.08

 

0.84 ± 0.67

< 0.001

-0.07 ± 0.06

0.212

0.78 ± 0.75

< 0.001

Smokers

4.39 ± 0.13

 

3.63 ± 0.10

 

3.63 ± 0.11

 

0.76 ± 0.10

< 0.001

0.00 ± 0.50

0.990

0.76 ± 0.10

< 0.001

Mean diff ± SEM

0.44 ± 0.16

0.006

0.53 ± 0.13

< 0.001

0.46 ± 0.14

0.002

-0.09 ± 0.12

0.996

0.07 ± 0.08

0.775

-0.01 ± 0.12

0.626

BI

      

OR (95% CI)

 

OR (95% CI)

 

OR (95% CI)

 

Non-smokers

71.1% ± 2.6%

 

24.1% ± 2.0%

 

35.7% ± 1.9%

 

0.13 (0.09;0.18)

< 0.001

1.75 (1.33;2.30)

< 0.001

0.23 (0.16;0.32)

< 0.001

Smokers

74.9% ± 2.9%

 

26.9% ± 1.8%

 

31.5% ± 1.7%

 

0.12 (0.08;0.19)

< 0.001

1.25 (0.99;1.58)

0.064

0.15 (0.11;0.23)

< 0.001

OR (95% CI)

1.21 (0.82;1.80)

0.342

1.15 (0.88;1.52

0.311

0.83 (0.66;1.04)

0.097

0.95 (0.54;1.66)

0.977

0.68 (0.41;1.13)

0.178

0.72 (0.50;1.02)

0.071

PI

      

OR (95% CI)

 

OR (95% CI)

 

OR (95% CI)

 

Non-smokers

63.8% ± 3.3%

 

24.3% ± 2.4%

 

37.9% ± 3.3%

 

0.18 (0.11;0.30)

< 0.001

1.90 (1.25;2.91)

0.001

0.35 (0.25;0.48)

< 0.001

Smokers

57.6% ± 3.4%

 

23.6% ± 2.4%

 

35.7% ± 4.0%

 

0.23 (0.15;0.33)

< 0.001

1.79 (1.30;2.47)

< 0.001

0.41 (0.26;0.63)

< 0.001

OR (95% CI)

0.77 (0.52;1.15)

0.201

0.96 (0.67;1.38)

0.826

0.90 (0.58;1.40)

0.654

1.24 (0.66;2.35)

0.700

0.94 (0.56;1.60)

0.963

0.17 (0.68;2.03)

0.776

PD ≤ 4 mm no BOP

      

OR (95% CI)

 

OR (95% CI)

 

OR (95% CI)

 

Non-smokers

24.8% ± 2.2%

 

67.3% ± 2.2%

 

52.9% ± 3.2%

 

6.22 (4.51;8.58)

< 0.001

0.54 (0.37;0.81)

0.001

3.40 (2.13;5;41)

< 0.001

Smokers

19.1% ± 2.4%

 

57.9% ± 3.0%

 

51.9% ± 3.4%

 

5.83 (3.90;8.74)

< 0.001

0.79 (0.62;1.00)

0.052

4.59 (2.96;7.13)

< 0.001

OR (95% CI)

0.71 (0.48;1.05)

0.084

0.67 (0.49;0.91)

0.011

0.96 (0.67;1.39)

0.835

0.94 (0.56;1.57)

0.954

1.44 (0.91;2.29)

0.154

1.35 (0.72;2.55)

0.511

  1. Probing depth (PD); Clinical attachment loss (CAL); Bleeding index (BI); Plaque index (PI); Marginal mean values and percentages are presented with standard errors. PD and CAL are presented in mm and analysed using linear regression models. BI and PI are presented as percentages, and differences and changes are presented as Odds ratios (OR) with 95% confidence intervals (CI), based on logistic regression analysis