Fig. 3

Histological findings. (a) The biopsy of the mucous membrane adjacent to the alveolar process revealed infiltration of histiocytes and neutrophils beneath the mucosa. The arrowhead indicates lumen occlusion (Haematoxylin and Eosin ×200). (b) The biopsy of the alveolar process showed fragments of nonvital lamellar bone (green arrowhead), which were devoid of osteoblasts and osteocytes and were surrounded by numerous neutrophils (black arrowhead) and bacterial aggregates (yellow arrowhead) (Haematoxylin and Eosin ×200). (c) The pathological findings of postoperative tissue were similar to those of previous biopsies, and osteonecrosis (green arrowhead), numerous neutrophils (black arrowhead) and bacterial aggregates (yellow arrowhead) were observed (Haematoxylin and Eosin ×200). (d) Arrowheads indicate bacterial aggregates inside the marrow cavity (Periodic Acid-Schiff staining ×100)