Table 1 Search strategy for databases included in the review

PubMed

((((((((Bioactive) OR (regenerative) OR (Pulp Capp*)) OR (pulp dress*)) OR (calcium silicate)) OR (non-degradable bioactive materials)) OR (degradable natural and synthetic tissue engineering scaffolds)) AND (pulpotomy)) AND ((“Tooth, Deciduous“[Mesh])) OR (“Dentition, Permanent“[Mesh]) AND (pulp) AND (“Histology“[MeSH Terms] OR “Clinical Trial“[Publication Type])) (y_10[Filter])

Scopus

( ( bioactive ) OR ( regenerative ) OR ( calcium AND silicate ) ) AND ( pulpotomy ) AND ( ( primary ) OR ( permanent ) AND ( teeth ) ) AND ( clinical ) AND ( LIMIT-TO ( SRCTYPE , “j" ) ) AND ( LIMIT-TO ( DOCTYPE , “ar" ) ) AND ( LIMIT-TO ( SUBJAREA , “DENT" ) ) AND ( LIMIT-TO ( PUBYEAR , 2023 ) OR LIMIT-TO ( PUBYEAR , 2022 ) OR LIMIT-TO ( PUBYEAR , 2021 ) OR LIMIT-TO ( PUBYEAR , 2020 ) OR LIMIT-TO ( PUBYEAR , 2019 ) OR LIMIT-TO ( PUBYEAR , 2018 ) OR LIMIT-TO ( PUBYEAR , 2017 ) OR LIMIT-TO ( PUBYEAR , 2016 ) OR LIMIT-TO ( PUBYEAR , 2015 ) OR LIMIT-TO ( PUBYEAR , 2014 ) OR LIMIT-TO ( PUBYEAR , 2013 ) OR LIMIT-TO ( PUBYEAR , 2012 ) ) AND ( LIMIT-TO ( LANGUAGE , “English" ) ) AND ( LIMIT-TO ( EXACTKEYWORD , “Human" ) OR LIMIT-TO ( EXACTKEYWORD , “Humans" ) )

Web of science

(((((((((((ALL=(Bioactive)) OR ALL=(regenerative)) OR ALL=(pulp capping)) OR ALL=(pulp dressing)) OR ALL=(calcium silicate)) OR ALL=(non-degradable bioactive materials))) OR ALL=(degradable natural and synthetic tissue engineering scaffolds))) AND ALL=(pulpotomy)) AND ALL=((Primary OR Permanent) AND (teeth))) AND ALL=((Histology OR Clinical))

Filters: from 2012–2023

ProQuest

(Bioactive OR regenerative) AND (pulpotomy) AND (primary OR permanent teeth) AND (clinical OR histological)

Applied filters: Last 10 years

Clinicaltrials.gov

Pulpotomy (as the condition)

Applied filters: Recruiting, Not yet recruiting, Active, not recruiting, Completed, Terminated Studies | Interventional Studies | pulpotomy | Start date from 01/01/2012 to 10/31/2023