Fig. 5

Correlations between oral microbiota in plaque or gingival crevicular fluid specimens and the changes of gingival index or plaque index. The microbiota changes among plaque specimens of all enrolled subjects after using toothpastes were determined by qPCR and were calculated with 2^-ΔΔCt method. (A, B) The correlations of A. actinomycetemcomitans (AA in A) or Campylobacter genus (B) with the changed gingival index (Δ gingival index) among plaque specimens were determined by with Spearman’s rank correlation analysis. (C, D) The correlations of Gemella genus with Δ gingival index (A) or with the changed plaque index (Δ plaque index) among gingival crevicular fluid specimens were also determined by with Spearman’s rank correlation analysis