Skip to main content

Table 2 Bacterial composition of plaques and gingival crevicular fluid (GCF) from gingivitis patients.

From: The impact of Lacticaseibacillus paracasei GMNL-143 toothpaste on gingivitis and oral microbiota in adults: a randomized, double-blind, crossover, placebo-controlled trial

 

Plaque

GCF

 

Placebo

GMNL-143

p-value

Placebo

GMNL-143

p-value

2-ΔΔCT

Mean ± SD

Mean ± SD

 

Mean ± SD

Mean ± SD

 

Total bacteria

0.95 ± 0.53

0.87 ± 0.34

0.8536

1.48 ± 1.64

1.08 ± 0.84

0.6441

Porphyromonas

5.83 ± 13.11

3.30 ± 8.52

0.4143

1.78 ± 2.34

1.75 ± 1.90

0.3028

Treponema

1.39 ± 1.70

2.31 ± 1.81

0.1167

1.72 ± 2.13

2.99 ± 3.60

0.1876

Tannerella

3.13 ± 4.93

1.16 ± 0.94

0.5879

1.59 ± 1.66

1.69 ± 1.45

0.3757

Filifactor

1.20 ± 0.46

1.37 ± 0.92

> 0.9999

1.73 ± 1.34

1.52 ± 0.99

0.9632

Aggregatibacter

2.24 ± 3.71

1.73 ± 3.06

0.7467

1.82 ± 2.68

1.53 ± 1.19

0.7119

Streptococcus mutans

1.34 ± 1.97

1.96 ± 2.22

0.1102

1.52v± 1.82

0.61 ± 0.63

0.0655

Porphyromonas gingivalis

1.22 ± 1.36

0.89 ± 0.81

0.7090

0.64 ± 0.47

1.03 ± 0.79

0.0984

Fusobacterium nucleatum

0.97 ± 0.56

1.21 ± 0.59

0.1270

ND

ND

ND

Aggregatibacter actinomycetemcomitans

1.58 ± 1.37

1.35 ± 2.11

0.2297

ND

ND

ND

Streptococcus

1.30 ± 0.88

0.87 ± 0.77

0.3755

1.08 ± 0.76

0.87 ± 0.63

0.1202

Haemophilus

1.61 ± 2.00

1.60 ± 2.05

0.8900

1.32 ± 1.46

1.33 ± 1.08

0.7820

Capnocytophaga

1.54 ± 1.53

1.49 ± 1.43

0.5416

1.65 ± 2.08

1.79 ± 1.51

0.6441

Gemella

1.31 ± 1.07

1.03 ± 0.73

0.3755

0.64 ± 0.55

0.90 ± 1.21

0.3028

Campylobacter

1.29 ± 1.73

2.41 ± 2.59

0.1754

1.44 ± 1.26

2.39 ± 2.09

0.1591

Granulicatella

0.69 ± 0.70

0.93 ± 0.91

0.7057

0.70 ± 0.66

1.36 ± 2.01

0.5171

  1. Bacterial composition was determined by the qPCR method and calculating the value of 2−ΔΔCt that reflected the fold change compared to the baseline of bacterial contents from plaque or GCF specimens
  2. Statistical analyses between GMNL®-143 and placebo toothpaste were performed by Wilcoxon signed-rank tes