Articles

Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation

During the process of deep decay, when decay approaches the pulp, an immune response is triggered inside the pulp, which activates the complement cascade. The effect of complement component 5a (C5a) on the dif...

Authors: Jie Liu, Xiaoling Wei, Junlong Hu, Xiaohan Tan, Xiaocui Kang, Li Gao, Ning Li, Xin Shi, Mengtong Yuan, Weiping Hu and Mingyue Liu

Trends of dental caries in permanent teeth among 12-year-old Chinese children: evidence from five consecutive national surveys between 1995 and 2014

Dental caries have a serious impact on general health and well-being; however, there is a lack of relevant data on the development trends of dental caries in permanent teeth among 12-year-old children in China...

Authors: Zhen Hu, Xiaojin Yan, Yi Song, Shang Ma, Jun Ma and Guangrong Zhu

Association between chronic periodontitis and the risk of Alzheimer’s disease: combination of text mining and GEO dataset

Although chronic periodontitis has previously been reported to be linked with Alzheimer's disease (AD), the pathogenesis between the two is unclear. The purpose of this study is to analyze and screen the relev...

Authors: Zhengye Jiang, Yanxi Shi, Wenpeng Zhao, Liwei Zhou, Bingchang Zhang, Yuanyuan Xie, Yaya Zhang, Guowei Tan and Zhanxiang Wang

Biofilm formation following chitosan-based varnish or chlorhexidine-fluoride varnish application in patients undergoing fixed orthodontic treatment: a double blinded randomised controlled trial

Orthodontic treatment poses an increased risk of plaque accumulation and demineralisation of enamel leading to white spot lesion around the brackets. This parallel arm trial aims to assess the degree of bacter...

Authors: Preethi Poornima, Jogikalmat Krithikadatta, Ratna Rachel Ponraj, Natanasabapathy Velmurugan and Anil Kishen

Comparison of digital and silicone impressions for single-tooth implants and two- and three-unit implants for a free-end edentulous saddle

The use of intraoral scanners (IOS) has facilitated the use of digital workflows for the fabrication of implant-supported prostheses not only for single missing teeth, but also for multiple missing teeth. Howe...

Authors: Koudai Nagata, Kei Fuchigami, Yurie Okuhama, Kana Wakamori, Hayato Tsuruoka, Toshifumi Nakashizu, Noriyuki Hoshi, Mihoko Atsumi, Katsuhiko Kimoto and Hiromasa Kawana

Application of first-order feature analysis of DWI-ADC in rare malignant mesenchymal tumours of the maxillofacial region

To research the first-order features of apparent diffusion coefficient (ADC) values on diffusion-weighted magnetic resonance imaging (DWI) in maxillofacial malignant mesenchymal tumours.

Authors: Baoting Yu, Chencui Huang, Shuo Liu, Tong Li, Yuyao Guan, Xuewei Zheng and Jun Ding

Does low dose of etoricoxib play pre-emptive analgesic effect in third molar surgery? A randomized clinical trial

How to prevent pain after the extraction of impacted teeth is a serious challenge for all patients. The purpose of this clinical trial was to investigate whether pre-emptive low dose of etoricoxib can reduce p...

Authors: Long Xie, Lei Sang and Zhi Li

Morphometry and displacement analysis of the upper lips following maxillary full-arch implant-supported fixed prostheses: a 3D morphometric study

With the emergence of three-dimensional (3D) integration technology, analysis of soft tissue displacement and morphological changes after maxillary full-arch implant-supported fixed prostheses can be performed...

Authors: Keyi Hao, Jia Luo, Ping Di, Yu Zhang and Ye Lin

The effects of removing dead bacteria by propidium monoazide on the profile of salivary microbiome

Oral microbiome played an important role in maintaining healthy state and might exhibit certain changes under circumstances of diseases. However, current microbiological research using sequencing techniques di...

Authors: Qidi Ren, Fangqiao Wei, Chao Yuan, Ce Zhu, Qian Zhang, Junkang Quan, Xiangyu Sun and Shuguo Zheng

What non-clinical factors influence the general dentist–specialist relationship in Canada?

The general dentist–specialist relationship is important for effective patient care and the professional environment. This study explores the non-clinical factors that may influence the general dentist–special...

Authors: Harpinder Kaur, Sonica Singhal, Michael Glogauer, Amir Azarpazhooh and Carlos Quiñonez

Ecological determinants of effect of a free pit and fissure sealant program in Shanxi, China, 2017–2018

The aim of this study is to explore the spatial heterogeneity of the retention of PFS in children aged 7–9 years in Shanxi Province, North China and investigate the risk factors associated with PFS retention.

Authors: Xiangyu Wang, Wenjuan Ren, Yufang Li, Bin Zhao, Tingting Yang, Ruxia Hou, Junming Li and Junyu Liu

A predictive nomogram: a cross-sectional study on a simple-to-use model for screening 12-year-old children for severe caries in middle schools

A nomogram is a tool that transforms complex regression equations into simple and visual graphs and enables clinicians and patients to conveniently compute output probabilities without needing medical knowledg...

Authors: Shaoying Duan, Meng Li, Jialiang Zhao, Huiyu Yang, Jinfeng He, Lei Lei, Ran Cheng and Tao Hu

Pattern of dental needs and advice on Twitter during the COVID-19 pandemic in Saudi Arabia

To compare and evaluate the influence of the COVID-19 outbreak on tweets related to dental treatment needs and advice of Saudi Twitter users in 2020 by comparing them to the same time-period in 2019.

Authors: Khalifa S. Al-Khalifa, Eman Bakhurji, Hassan S. Halawany, Esraa M. Alabdurubalnabi, Wejdan W. Nasser, Ashwin C. Shetty and Shazia Sadaf

The prevalence of denture stomatitis in cigarette and hookah smokers and opium addicts: findings from Rafsanjan Cohort Study

The aim of this study was to investigate the association of denture stomatitis prevalence with cigarette, hookah and opium consumption and also dose–response relationship between the cigarette smoking duration...

Authors: Farimah Sardari, Parvin Khalili, Hamid Hakimi, Saadat Mahmoudaghaei and Pouya Abedi

Real-time co-site optical microscopy study on the morphological changes of the dentine’s surface after citric acid and sodium hypochlorite: a single-tooth model

To this day, the effects of sodium hypochlorite and chelating agents on the smear layer and on the dentine’s surface, remain not fully examined. The study is aimed to analyze the dentine's surface treated with...

Authors: Wojciech Wilkoński, Lidia Jamróz-Wilkońska, Szczepan Zapotoczny, Janusz Opiła and Luciano Grandino

Oral health seeking behaviors of adults in Nebbi District, Uganda: a community-based survey

Dental health is often neglected by the majority of the population and has contributed to the global burden of oral diseases. We assessed awareness, utilization and barriers to seeking oral health care among a...

Authors: Juliet Ocwia, Ronald Olum, Pamela Atim, Florence Laker, Jerom Okot, Senai Goitom Sereke, Joseph Baruch Baluku, Sarah Kiguli and Felix Bongomin

Clinical relevance of interdental papilla biopsy in chronic erosive gingivitis (desquamative gingivitis): retrospective bicentric study of 148 specimens

Chronic erosive gingivitis, also called desquamative gingivitis, defines a clinical picture that can be generated by several inflammatory and immune diseases. Pathology is therefore essential for the different...

Authors: Frédérick Gaultier, Anne-laure Ejeil, Sébastien Jungo, Saskia Ingen-Housz-Oro, François Le Pelletier de Clatigny, Gogly Bruno, Philippe Pirnay, Fadel Bellakhdar and Sophie-Myriam Dridi

Associations between dental care approachability and dental attendance among women pregnant with an Indigenous child: a cross-sectional study

Oral health during pregnancy is vital for both mother and child. Indigenous Australians face many barriers in accessing dental care. Service approachability is one of the key domains in accessing health servic...

Authors: Yuan Gao, Xiangqun Ju and Lisa Jamieson

Prevalence of dental caries in Pakistan: a systematic review and meta-analysis

Optimum oral health is impossible to achieve without managing dental caries. The first step to manage dental caries at a community level is to know its prevalence and trend. Unfortunately, the prevalence of de...

Authors: Ammar Ahmed Siddiqui, Freah Alshammary, Mushir Mulla, Saad M. Al-Zubaidi, Eman Afroze, Junaid Amin, Salman Amin, Sameer Shaikh, Ahmed A. Madfa and Mohammad Khursheed Alam

Prevalence of complex root canal morphology in the mandibular first and second premolars in Thai population: CBCT analysis

Mandibular premolars demonstrate high variability in root canal morphology, especially mandibular first premolars. The purposes of this study were to determine the prevalence of root canal configurations of ma...

Authors: Paramee Thanaruengrong, Sirinya Kulvitit, Mettachit Navachinda and Pornkawee Charoenlarp

Morphometric and histomorphometric evaluations of high-purity macro/microporous beta-tricalcium phosphate in maxillary sinus floor elevation: preliminary results on a retrospective, multi-center, observational study

The present study examined the effectiveness of high-purity macro/microporous beta-tricalcium phosphate (HPMM β-TCP) as a bone grafting material for maxillary sinus floor elevation by morphometric, histopathol...

Authors: Atsushi Fujita, Chonji Fukumoto, Tomonori Hasegawa, Yuta Sawatani and Hitoshi Kawamata

Effect of epigallocatechin gallate on dental biofilm of Streptococcus mutans: An in vitro study

Streptococcus mutans (S. mutans) plays a major role in the formation of dental caries. The aim of this study was to examine the effect of the green tea polyphenol, epigallocatechin gallate (EGCG), on biofilm for...

Authors: Mor Schneider-Rayman, Doron Steinberg, Ronit Vogt Sionov, Michael Friedman and Miriam Shalish

Validity and reliability of new instruments for measuring patient satisfaction with removable dentures, Arabic Version

The psychometric properties of self-administered instruments for measuring patient satisfaction with removable dentures should be tested before inviting patients to express their opinions. This study aimed to ...

Authors: Ahmad Al Jaghsi, Musab Saeed, Salem Abu Fanas, Ahmed Yaseen Alqutaibi and Torsten Mundt

Associations of early childhood caries with salivary beta defensin-3 and childhood anemia: a case–control study

Human beta defensin-3 (HβD-3) is an antimicrobial peptide present in saliva that protects tooth surfaces from microbial attack. These peptides are part of innate immunity so levels may be affected by different...

Authors: Sanam Faheem, Shahida Maqsood, Arshad Hasan, Fouzia Imtiaz, Faheem Shaikh and Waqas Ahmed Farooqui

Outbreak of oral ulcers (glossitis) among the students of three central schools under Tsirang district Bhutan, 2018

Nutritional deficiencies are common worldwide and is most notable in low and middle income countries. In the early weeks of September 2018, oral sores mostly affecting the tongue were reported in three central...

Authors: Tshewang Gyeltshen, Lham Dorji, Leki Dorj and Kuenga Choden

Influence of sagittal root positions on the stress distribution around custom-made root-analogue implants: a three-dimensional finite element analysis

Stress concentration may cause bone resorption even lead to the failure of implantation. This study was designed to investigate whether a certain sagittal root position could cause stress concentration around ...

Authors: Chunping Lin, Hongcheng Hu, Junxin Zhu, Yuwei Wu, Qiguo Rong and Zhihui Tang

Knowledge and awareness of dental implants among Syrian refugees: a cross sectional study in Zaatari camp

The popularity of implant dentistry is increasing dramatically, but the success of implant treatment depends on a patient’s knowledge and expectations.

Authors: Nesreen A. Salim, Fatima Hafedh Meyad, Mariam Mohammad Al-Abdallah, Motasum Abu-Awwad and Julian D. Satterthwaite

A randomised clinical study investigating efficacy of a stannous fluoride toothpaste in improving gingival health after 3 weeks’ use

This examiner-blind, stratified, parallel study aimed to evaluate the anti-gingivitis efficacy of a non-aqueous (anhydrous) 0.454% w/w stannous fluoride toothpaste (‘Test’) versus a sodium monofluorophosphate ...

Authors: Amina Acherkouk, Nisha Patel, Andrew Butler and Pejmon Amini

Do preterm-born adolescents have a poorer oral health-related quality of life?

To evaluate oral health-related quality of life (OHRQoL) over a period of five years using the Oral Health Impact Profile (OHIP-14) questionnaire in a population of Swedish adolescents born preterm and full term.

Authors: Susanne Brogårdh-Roth, Liselotte Paulsson, Pernilla Larsson and Ewacarin Ekberg

Correction to: Dental vulnerability scale in primary health care: evidence of content and structure internal validity

Authors: Danielle da Costa Palacio, Flavio Rebustini, Daniele Boina de Oliveira, João Peres Neto, Wander Barbieri, Thais Paragis Sanchez, Ana Carolina Cintra Nunes Mafra, Daiana Bonfim, Camila Nascimento Monteiro, Valmir Vanderlei Gomes Filho, Danielle Viana Ribeiro, Leandro Marsico Loschiavo, João Luiz Miraglia and Antonio Carlos Pereira

Changes in denture retention with denture adhesives and oral moisturizers for the oral cavity: an in vitro study

It is difficult to maintain complete dentures during meals in place. This in vitro study aimed to assess changes in denture retention between rest and function using denture adhesives and oral moisturizers in ...

Authors: Naoya Ikemura, Yuji Sato, Junichi Furuya, Osamu Shimodaira, Kana Takeda, Takuya Kakuta, Kunihito Yamane and Noboru Kitagawa

Concomitant bilateral mandibular cemento-ossifying fibroma and cementoblastoma: case report of an extremely rare occurrence

Cemento-ossifying fibroma (COF) and cementoblastoma (CB) are rare benign odontogenic tumors with a predilection for the mandible. Cemento-ossifying fibroma is a fibro-osseous lesion that originates in the toot...

Authors: Madiha Bilal Qureshi, Muhammad Usman Tariq, Jamshid Abdul-Ghafar, Muhammad Raza and Nasir Ud Din

The economic benefits of increased sugar-free chewing gum in China: a budget impact analysis

To analyze the potential cost savings in dental care associated with increased sugar-free gum (SFG) use among Chinese teenagers and adults.

Authors: Shuo Du, Chunzi Zhang, Wenhui Wang, Jian Liu, Chao Yuan, Yizhen Yu, Qing Chang, Shanshan Zhang and Yan Si

Effects of remote digital monitoring on oral hygiene of orthodontic patients: a prospective study

Remote digital monitoring during orthodontic treatment can help patients in improving their oral hygiene performance and reducing the number of appointments due to emergency reasons, especially in time of COVI...

Authors: Linda Sangalli, Fabio Savoldi, Domenico Dalessandri, Stefano Bonetti, Min Gu, Alberto Signoroni and Corrado Paganelli

“What are we doing to our babies’ teeth?” Barriers to establishing oral health practices for Indigenous children in South Australia

During the 1970s, optimal oral health was experienced more frequently amongst Indigenous children in Australia than their non-Indigenous counterparts. As a result of public health interventions targeting oral ...

Authors: Brianna Poirier, Joanne Hedges, Lisa Smithers, Megan Moskos and Lisa Jamieson

Cost-utility analysis of an implant treatment in dentistry

When dealing with the replacement of one missing tooth, the patient has the option of choosing between different types of treatment interventions. Several important factors play a role in his decision-making p...

Authors: Johana Losenická, Ondřej Gajdoš and Vojtěch Kamenský

Temporomandibular dysfunction experience is associated with oral health-related quality of life: an Australian national study

There are very few studies of the association between temporomandibular dysfunction (TMD) and oral health-related quality of life (OHRQoL) in a representative sample from the Asia–Pacific region. Accordingly, ...

Authors: Kamal Hanna, Rahul Nair, Najith Amarasena, Jason M. Armfield and David S. Brennan

Tooth alignment and pain experience with A-NiTi versus Cu-NiTi: a randomized clinical trial

Nickel-titanium (NiTi) archwires are routinely used for initial leveling and alignment of teeth in orthodontic treatment. This study aimed to clinically compare the level of pain and tooth alignment in orthodo...

Authors: Fatemeh Azizi, Aida Extiari and Mohammad Moslem Imani

Predictors of self-rated oral health in Canadian Indigenous adults

The purpose of this study was to: (1) compare oral health indicators between Indigenous adults and the general population and (2) examine the predictors of poor self-rated oral health in the Indigenous populat...

Authors: Ahmed Hussain, Sheyla Bravo Jaimes and Alexander M. Crizzle

A new comprehensive oral health literacy scale: development and psychometric evaluation

It has been widely accepted that oral health status is related to oral health literacy. The need to measure oral health literacy has led to the development of measurement instruments. This study aimed to devel...

Authors: Yue Sun, Jing Sun, Yan Zhao, Aixiao Cheng and Junhong Zhou

Evaluating the presence of IAN injury in patients with juxta-apical radiolucency after third molar surgery: a retrospective cohort study

Juxta-apical radiolucency (JAR) has been presented as a radiographic sign, suggestive of the IAN injury through third molar surgery. This study aimed to evaluate the relation of JAR with IAN injury in cone-bea...

Authors: Mahvash Hasani, Nasim Razavi, Abdolaziz Haghnegahdar and Motahhareh Zarifi

Genotoxicity and cytotoxicity of cone beam computed tomography in children

Dental radiographs are essential tools for diagnosis. However, there are significant concerns about the dangerous effect of radiation especially on children. The aim of this study was to evaluate genotoxicity ...

Authors: Doua H. Altoukhi, Sumer Alaki, Eman El Ashiry, Osama Nassif and Dania Sabbahi

B cell activating factor regulates periodontitis development by suppressing inflammatory responses in macrophages

B cell activating factor (BAFF) is a member of the tumor necrosis factor (TNF) superfamily with immunomodulatory effects on both innate and adaptive immune responses. Periodontitis is an inflammatory disease c...

Authors: Lixia Wang, Tianyi Zhang, Zheng Zhang, Zihan Wang, Yu-Jie Zhou and Zuomin Wang

Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review

A growing body of evidence suggests a role for oral bacteria in lung infections. This systematic review aimed to analyse the association between poor periodontal status and the frequency of chronic obstructive...

Authors: Niamh Kelly, Lewis Winning, Christopher Irwin, Fionnuala T. Lundy, Dermot Linden, Lorcan McGarvey, Gerard J. Linden and Ikhlas A. El Karim

Root canal morphology and variations in mandibular second molars: an in vivo cone-beam computed tomography analysis

The purpose of this study was to determine the anatomical variations of the root canal system of mandibular second molars using cone-beam computed tomography (CBCT).

Authors: Francisco Gomez, Gisbeli Brea and Jose Francisco Gomez-Sosa

Multiple root canals in the maxillary molar: an unusual case report

The objective of this report was to highlight the importance of using a dental operating microscope (DOM) to locate supernumerary canals and diagnose variations in root canals using cone-beam computed tomograp...

Authors: Yao Lin, Yan Xiang, Xiaoling Chen, He Wang, Na Cao, Xiaoman Xu, Yangan Zhang and Zhaojun Wu

Surface roughness and color measurements of glazed or polished hybrid, feldspathic, and Zirconia CAD/CAM restorative materials after hot and cold coffee immersion

The purpose of this study evaluates and compares the effect of surface roughness (Ra) and color stability on computer-aided design/computer-aided manufacturing (CAD/CAM) hybrid resin (Vita Enamic), feldspathic...

Authors: Lujain I. Aldosari, Abdulkhaliq A. Alshadidi, Amit Porwal, Nasser M. Al Ahmari, Mohammed M. Al Moaleem, Ahmed M. Suhluli, Mansoor Shariff and Ahmed O. Shami

Dental vulnerability scale in primary health care: evidence of content and structure internal validity

Access to oral health services remains a challenge in the Brazilian healthcare system, especially in the primary health care setting, where the use of a risk stratification tool that could identify individuals...

Authors: Danielle da Costa Palacio, Flavio Rebustini, Daniele Boina de Oliveira, João Peres Neto, Wander Barbieri, Thais Paragis Sanchez, Ana Carolina Cintra Nunes Mafra, Daiana Bonfim, Camila Nascimento Monteiro, Valmir Vanderlei Gomes Filho, Danielle Viana Ribeiro, Leandro Marsico Loschiavo, João Luiz Miraglia and Antonio Carlos Pereira

Influence of active versus passive parental presence on the behavior of preschoolers with different intelligence levels in the dental operatory: a randomized controlled clinical trial

Dental fear and anxiety still pose the most common factors proposed for the child’s negative behavior in the dental operatory. Intelligence has an impact on the children’s communication, feelings, and responsi...

Authors: Thiyezen Abdullah AlDhelai, Amani Mohamed Khalil, Yasmine Elhamouly and Karin M. L. Dowidar

Nasopalatine duct cyst with sebaceous differentiation: a rare case report with literature review

The aim of this study was to report a rare case of nasopalatine duct cyst with sebaceous differentiation. Further, a systematic search of the literature was performed to identify studies reporting patients wit...

Authors: Han-Gyeol Yeom, Jae-Hyun Kang, Sun-Ung Yun and Jung-Hoon Yoon